Results 91 to 100 of about 8,199 (263)

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

D12 Behavior of Vortex Cavity in Strong Longitudinal Vortex

The Proceedings of Conference of Kyushu Branch, 2007
Saki MATSUO, Satoshi WATANABE, Akinori FURUKAWA   +2 more
openaire   +2 more sources

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Numerical Study of Surface Flow for Ahmed Body in Crosswind Conditions

Automotive Experiences
This study investigates standard vehicles' flow behavior and drag during crosswind conditions by a numerical approach. The model is a half-scaled Ahmed body with a slant angle of 25°. Reynolds Average Navier-Stokes equations with turbulent model k-ω SST
Pham Van Duy, Le Dinh Anh, Dinh Cong Truong, Tran The Hung, Do Van Minh   +4 more
doaj   +1 more source

Experimental Study on Gas-Solid Flow in the Spouted Bed under Longitudinal Vortex Effect. [PDF]

ACS Omega, 2019
Wu F, Che X, Duan H, Shang L, Ma X, Wang G, Hui Z.   +6 more
europepmc   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

CFD Simulation and Optimization of Mixing Behaviors in a Spouted Bed with a Longitudinal Vortex. [PDF]

ACS Omega, 2019
Wu F, Bai J, Zhang J, Zhou W, Ma X.
europepmc   +1 more source

Magnetotransport Signatures of Spin–Orbit Coupling in High‐Temperature Cuprate Superconductors

Advanced Science, EarlyView.
Large angle‐dependent magnetoresistance and planar Hall effects emerge at the superconducting transition of YBa2Cu3O7−x$\mathrm{YBa_2Cu_3O_{7-x}}$ thin films. These anomalous transport signatures, absent in the normal state, point to spin‐polarized quasiparticle dynamics enabled by an unexpected spin–orbit coupling landscape in cuprate superconductors,
Aleix Barrera, Huidong Li, Thomas Gunkel, Jordi Alcalá, Silvia Damerio, Can Onur Avci, Anna Palau   +6 more
wiley   +1 more source

Methods for Prediction of Leading Aircraft Wake Vortex Hazard Zone Based on Receiving ADS‑B In Data

Nanjing Hangkong Hangtian Daxue Xuebao
To address the risk management requirements of wake vortex encounters during following aircraft operations， this study proposes an airborne prediction method for wake vortex hazard zones using flight dynamic data of leading aircraft received through ...
WEI Zhiqiang, LIU Chang
doaj   +1 more source