Results 51 to 60 of about 73,960 (240)

Two-loop infrared renormalization with on-shell methods

open access: yesEuropean Physical Journal C: Particles and Fields, 2023
Within the framework proposed by Caron-Huot and Wilhelm, we give a recipe for computing infrared anomalous dimensions purely on-shell, efficiently up to two loops in any massless theory.
Pietro Baratella   +3 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Quasinormal modes of a massive scalar field nonminimally coupled to gravity in the spacetime of self-dual black hole

open access: yesEuropean Physical Journal C: Particles and Fields, 2021
In this work, we investigate the quasinormal modes for a massive scalar field with a nonminimal coupling with gravity in the spacetime of a loop quantum black hole, known as the self-dual black hole.
J. S. Santos, M. B. Cruz, F. A. Brito
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Loop-free verification of termination of derivation for a fragment of dynamic logic

open access: yesLietuvos Matematikos Rinkinys, 2008
A fragment of a deterministic propositional dynamic logic (DPDL, in short) is considered The language of considered fragment contains propositional symbols, action constants, action operator (repetition) and logical symbols.
Regimantas Pliuškevičius
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Management Process of a Frequency Response Flight Test for Rotorcraft Flying Qualities Evaluation

open access: yesJournal of Aerospace Technology and Management, 2016
This paper applies the frequency response methodology to characterize and analyze the flying qualities of longitudinal and lateral axes of a rotary-wing aircraft, AS355-F2. Using the results, it is possible to check the suitability of the aircraft in
João Otávio Falcão Arantes Filho   +1 more
doaj   +2 more sources

Graviton propagator in a 2-parameter family of de Sitter breaking gauges

open access: yesJournal of High Energy Physics, 2019
We formulate the graviton propagator on de Sitter background in a 2-parameter family of simple gauges which break de Sitter invariance. Explicit results are derived for the first order perturbations in each parameter.
D. Glavan   +3 more
doaj   +1 more source

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