Results 61 to 70 of about 830,140 (297)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Perturbative four-point functions in planar N = 4 $$ \mathcal{N}=4 $$ SYM From hexagonalization
Journal of High Energy Physics, 2019 We use hexagonalization to compute four-point correlation functions of long BPS operators with special R-charge polarizations. We perform the computation at weak coupling and show that at any loop order our correlators can be expressed in terms of single
Frank Coronado
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Generalizing completeness results for loop checks in logic programming
Theoretical Computer Science, 1992 Loop checking is one of the fundamental problems encountered during the search of effective algorithms for logic programming. This complex problem cannot be solved in full generality (even in absence of function symbols). In \textit{R. N. Bol, K. R. Apt} and \textit{J. W. Klop} [ Theor. Comput. Sci. 86, No.
openaire +3 more sources
Sampling Loop Test Check Evaluation of Secondary System based on VAE-WSVM Data Mining
Zhongguo dianliAnalyze the hidden dangers existing in the sampling circuit of the secondary system, and in view of the defects that the existing methods are difficult to obtain large amount of data, based on the historical measurement data, the variational autoencoder ...
Xiangguo YIN +4 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Loop is delighted and honoured to announce that poet and playwright Adam Wyeth, who lives and works in Dublin, is as of June 2024 a patron of Loop. We look forward to continuing our conversation with Adam, begun at the excellent 2024 SAES Congress at ...
The LOOP team
core +1 more source
One loop in D = 11 vs D = 10: 4-point check
Journal of High Energy PhysicsThe one-loop correction to eleven-dimensional supergravity involves a cubically divergent term t 8 t 8 R 4, with four Riemann tensors. A similar term (with finite coefficient) has been argued to be present in the M-theory effective action. It is expected
Aviral Aggarwal +4 more
doaj +1 more source
A tale of two exponentiations in N=8 supergravity
Physics Letters B, 2019 The structure of scattering amplitudes in supergravity theories continues to be of interest. Recently, the amplitude for 2→2 scattering in N=8 supergravity was presented at three-loop order for the first time.
Paolo Di Vecchia +5 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source