Results 81 to 90 of about 79,255 (279)

A Robust BAO Extractor

open access: yes, 2017
We define a procedure to extract the oscillating part of a given nonlinear Power Spectrum, and derive an equation describing its evolution including the leading effects at all scales.
Noda, Eugenio   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A New Rational Algorithm for View Updating in Relational Databases

open access: yes, 2014
The dynamics of belief and knowledge is one of the major components of any autonomous system that should be able to incorporate new pieces of information.
Behrend, Andreas   +1 more
core   +1 more source

Demonstration of the Equivalence of Soft and Zero-Bin Subtractions [PDF]

open access: yes, 2007
Calculations of collinear correlation functions in perturbative QCD and Soft-Collinear Effective Theory (SCET) require a prescription for subtracting soft or zero-bin contributions in order to avoid double counting the contributions from soft modes.
Ahmad Idilbi   +3 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Unification of the General Non-Linear Sigma Model and the Virasoro Master Equation [PDF]

open access: yes, 1997
The Virasoro master equation describes a large set of conformal field theories known as the affine-Virasoro constructions, in the operator algebra (affine Lie algebra) of the WZW model, while the Einstein equations of the general non-linear sigma model ...
de Boer, J., Halpern, M. B.
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Loop-free verification of termination of derivation for a fragment of dynamic logic

open access: yesLietuvos Matematikos Rinkinys, 2008
A fragment of a deterministic propositional dynamic logic (DPDL, in short) is considered The language of considered fragment contains propositional symbols, action constants, action operator (repetition) and logical symbols.
Regimantas Pliuškevičius
doaj   +1 more source

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