Results 91 to 100 of about 59,217 (275)

Globally consistent dense 3D reconstruction with loop closure under fast camera motion

open access: yesGeo-spatial Information Science
This paper introduces a novel globally consistent dense RGB-D SLAM system designed to address the challenges of online dense reconstruction under fast camera motion.
Haigang Sui   +7 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Complications associated with loop ileostomy reversal delayed greater than twelve months

open access: yesScientific Reports
Diverting loop ileostomy is performed after colectomy to allow for anastomotic healing, and prevention of pelvic sepsis when an anastomotic leak occurs.
Jinman Cai   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Closure of mitral paravalvular defects without performing an arteriovenous loop: a case series of fourteen patients

open access: yesAdvances in Interventional Cardiology, 2017
Introduction: The arteriovenous (AV) loop is recommended when further support is needed during paravalvular leak (PVL) closure. Aim: We report the feasibility and safety of mitral PVL closure without constructing an AV loop, based on a single ...
Alev Kilicgedik   +7 more
doaj   +1 more source

Ultra-Wideband Aided Fast Localization and Mapping System

open access: yes, 2017
This paper proposes an ultra-wideband (UWB) aided localization and mapping system that leverages on inertial sensor and depth camera. Inspired by the fact that visual odometry (VO) system, regardless of its accuracy in the short term, still faces ...
Nguyen, Thien-Minh   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Loop Closure Detection with CNN in RGB-D SLAM for Intelligent Agricultural Equipment

open access: yesAgriculture
Loop closure detection plays an important role in the construction of reliable maps for intelligent agricultural machinery equipment. With the combination of convolutional neural networks (CNN), its accuracy and real-time performance are better than ...
Haixia Qi   +3 more
doaj   +1 more source

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