Results 111 to 120 of about 162,676 (316)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
A Semantic Spatial Structure-Based Loop Detection Algorithm for Visual Environmental Sensing
Remote SensingLoop closure detection is an important component of the Simultaneous Localization and Mapping (SLAM) algorithm, which is utilized in environmental sensing.
Xina Cheng +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
2D LiDAR SLAM Back-End Optimization with Control Network Constraint for Mobile Mapping
Sensors, 2018 Simultaneous localization and mapping (SLAM) has been investigated in the field of robotics for two decades, as it is considered to be an effective method for solving the positioning and mapping problem in a single framework.
Jingren Wen +5 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Generating Schemata of Resolution Proofs
, 2011 Two distinct algorithms are presented to extract (schemata of) resolution proofs from closed tableaux for propositional schemata. The first one handles the most efficient version of the tableau calculus but generates very complex derivations (denoted by ...
Aravantinos, Vincent, Peltier, Nicolas
core +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Polly's Polyhedral Scheduling in the Presence of Reductions
, 2015 The polyhedral model provides a powerful mathematical abstraction to enable effective optimization of loop nests with respect to a given optimization goal, e.g., exploiting parallelism.
Benaissa, Zino +3 more
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