Results 81 to 90 of about 162,676 (316)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Triangle Descriptor Loop Detection Method Based on Faster-LIO [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This paper introduces an enhanced approach to loop closure detection in Simultaneous Localization and Mapping (SLAM) by integrating the Faster-LIO framework with Stable Triangle Descriptors (STD).
S. Wang, H. Huang, J. Yang, J. Bian, S. Jiang   +4 more
doaj   +1 more source

Loop-closure detection by LiDAR scan re-identification

2020 25th International Conference on Pattern Recognition (ICPR), 2021
In this work, loop-closure detection from LiDAR scans is defined as an image re-identification problem. Reidentification is performed by computing Euclidean distances of a query scan to a gallery set of previous scans. The distances are computed in a feature embedding space where the scans are mapped by a convolutional neural network (CNN). The network
Peltomäki, Jukka, Ni, Xingyang, Puura, Jussi, Kämäräinen, Joni Kristian, Huttunen, Heikki   +4 more
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Place Recognition with Memorable and Stable Cues for Loop Closure of Visual SLAM Systems

Robotics, 2022
Visual Place Recognition (VPR) is a fundamental yet challenging task in Visual Simultaneous Localization and Mapping (V-SLAM) problems. The VPR works as a subsystem of the V-SLAM.
Rafiqul Islam, Habibullah Habibullah
doaj   +1 more source

JigsawNet: Shredded Image Reassembly using Convolutional Neural Network and Loop-based Composition

, 2018
This paper proposes a novel algorithm to reassemble an arbitrarily shredded image to its original status. Existing reassembly pipelines commonly consist of a local matching stage and a global compositions stage.
Le, Canyu, Li, Xin
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

All Transients, All the Time: Real-Time Radio Transient Detection with Interferometric Closure Quantities

, 2012
We demonstrate a new technique for detecting radio transients based on interferometric closure quantities. The technique uses the bispectrum, the product of visibilities around a closed-loop of baselines of an interferometer.
Baars, Booth, Briggs, Casey J. Law, Clark, Condon, Cornwell, Geoffrey C. Bower, Hallinan, Hallinan, Law, Lazio, Lomnicki, Macquart, Macquart, McLaughlin, Parsons, Perley, Pfahl, Siemion, Wharton   +20 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source