Results 41 to 50 of about 883,617 (266)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Is Ileostomy an Obligation Following Rectal Resection? The Role of Rectal Tube Instead of Ileostomy
Bezmiâlem Science, 2023 Objective:In laparoscopic distal colon surgery, diverting ileostomy is often used to improve the anastomosis leakage and eliminate the need for secondary surgery. However, complications related to the stoma and its closure have led to new searches.
Ersin GÜNDOĞAN +2 more
doaj +1 more source
Development of biometric systems for passenger identification based on noise-resistant coding means
Научный вестник МГТУ ГА, 2021 The paper deals with the issues of using the biometric technologies to establish identity of a passenger. The purpose of the article is to analyze the techniques of enhancing reliability of various biometric identification facilities by means of using ...
A. A. Gladkikh +2 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Distribution and Research of Loop Speed Codes under IATP Fallback Mode
机车电传动, 2014 Aim to the present condition that signal system for urban rail transits project mostly was based on moving block train trafficcontrol system (CBTC) and appropriate fallback mode was taken into consideration for the CBTC systems in most cities ...
YANGHai-peng, SONGYan
doaj
Improving Thermostability of GH11 Xylanase XynASP by the Design of Loop Region
Crystals, 2022 Highly flexible loop regions can affect the structure-function relationship of enzymes. In this study, to reveal the effect of the loop on the thermal stability of GH11 xylanase XynASP from Aspergillus saccharolyticus JOP 1030-1, three mutants (T41V ...
Tongbiao Li +6 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Applied Sciences, 2023 The purpose of this study was to compare the mechanical efficacies of the various loop springs in the extraction space closure. The long-term movement of the teeth was simulated by the finite element method.
Renpei Harada +6 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source