Results 51 to 60 of about 939,936 (265)

Is Ileostomy an Obligation Following Rectal Resection? The Role of Rectal Tube Instead of Ileostomy

open access: yesBezmiâlem Science, 2023
Objective:In laparoscopic distal colon surgery, diverting ileostomy is often used to improve the anastomosis leakage and eliminate the need for secondary surgery. However, complications related to the stoma and its closure have led to new searches.
Ersin GÜNDOĞAN   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Watching Genes Loop the Loop

open access: yesPLoS Biology, 2013
Most cells of a given species contain essentially the same complement of genes, yet individual genetically identical cells can assume dramatically different appearances and behaviours. This is achieved largely by the regulation of the transcription of individual genes, orchestrated by the specific binding of proteins to nearby sites in the genome—a ...
openaire   +4 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A Full-Body IMU-Based Motion Dataset of Daily Tasks by Older and Younger Adults

open access: yesScientific Data
This dataset (named CeTI-Age-Kinematics) fills the gap in existing motion capture (MoCap) data by recording kinematics of full-body movements during daily tasks in an age-comparative sample with 32 participants in two groups: older adults (66–75 years ...
Loreen Pogrzeba   +6 more
doaj   +1 more source

Loops of loops expansion in the amplituhedron

open access: yesJournal of High Energy Physics
Abstract We study a novel geometric expansion for scattering amplitudes in the planar sector of $$ \mathcal{N} $$ N = 4 super Yang-Mills theory, in the context of the Amplituhedron which reproduces the all-loop integrand ...
Brown, Taro   +3 more
openaire   +4 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Recursion Versus Iteration with the List as a Data Structure

open access: yesInformatics in Education, 2007
A reversible sequence of steps from the specification of the algorithm and the mathematical definition of the recurrent solution through the recursive procedure, the tail recursive procedure and finally to the iteration procedure, is shown.
Izabella FOLTYNOWICZ
doaj   +1 more source

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