Results 61 to 70 of about 1,578,241 (302)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The double loop mattress suture [PDF]
, 2014 © 2014 The Authors http://creativecommons.org/licenses/by/3.0/ An interrupted stitch type with favorable tissue characteristics will reduce local wound complications.
Biddlestone, John +3 more
core +1 more source
Loop, Floyd D. -- 1975-93 -- Correspondence, Individual -- letter, 1990-07-25
, 1990 Letter from Loop, Floyd D. to Sabin, Albert B.
Loop, Floyd D.
core +1 more source
A METHOD TO PREDICT EDGE STRANDS IN BETA-SHEETS FROM PROTEIN SEQUENCES
Computational and Structural Biotechnology Journal, 2013 There is a need for rules allowing three-dimensional structure information to be derived from protein sequences. In this work, consideration of an elementary protein folding step allows protein sub-sequences which optimize folding to be derived for any ...
Antonin Guilloux +2 more
doaj +1 more source
HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence
Molecular Systems Biology, 2021 Spatial organization and gene expression of mammalian chromosomes are maintained and regulated in conjunction with cell cycle progression. This is perturbed once cells enter senescence and the highly abundant HMGB1 protein is depleted from nuclei to act ...
Konstantinos Sofiadis +16 more
doaj +1 more source
Journal of Information Technology, 2020 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Loop, Floyd D. -- 1975-93 -- Correspondence, Individual -- letter, 1984-03-13
, 1984 Letter from Loop, Floyd D. to Sabin, Albert B.
Loop, Floyd D.
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Loop is delighted and honoured to announce that poet and playwright Adam Wyeth, who lives and works in Dublin, is as of June 2024 a patron of Loop. We look forward to continuing our conversation with Adam, begun at the excellent 2024 SAES Congress at ...
The LOOP team
core +1 more source