Results 71 to 80 of about 3,154,230 (297)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bilateral Tortuous External Iliac Artery: An Unusual Variation [PDF]
Bilateral tortuosity in the external iliac arteries is a rare finding in the cadavers. We report highly tortuous external iliac arteries of both the sides in a 60-year-old male cadaver noted during routine dissection. Left external iliac artery had a ‘U’
Rohini Motwani +2 more
doaj +1 more source
An Analytic Result for the Two-Loop Hexagon Wilson Loop in N = 4 SYM
In the planar N=4 supersymmetric Yang-Mills theory, the conformal symmetry constrains multi-loop n-edged Wilson loops to be basically given in terms of the one-loop n-edged Wilson loop, augmented, for n greater than 6, by a function of conformally ...
A Brandhuber +44 more
core +1 more source
Most cells of a given species contain essentially the same complement of genes, yet individual genetically identical cells can assume dramatically different appearances and behaviours. This is achieved largely by the regulation of the transcription of individual genes, orchestrated by the specific binding of proteins to nearby sites in the genome—a ...
openaire +4 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Loops of loops expansion in the amplituhedron
Abstract We study a novel geometric expansion for scattering amplitudes in the planar sector of $$ \mathcal{N} $$ N = 4 super Yang-Mills theory, in the context of the Amplituhedron which reproduces the all-loop integrand ...
Brown, Taro +3 more
openaire +4 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Recursion Versus Iteration with the List as a Data Structure
A reversible sequence of steps from the specification of the algorithm and the mathematical definition of the recurrent solution through the recursive procedure, the tail recursive procedure and finally to the iteration procedure, is shown.
Izabella FOLTYNOWICZ
doaj +1 more source
Holomorph of generalized Bol loops II
The notion of the holomorph of a generalized Bol loop (GBL) is characterized afresh. The holomorph of a right inverse property loop (RIPL) is shown to be a GBL if and only if the loop is a GBL and some bijections of the loop are right (middle) regular ...
Jaíyéolá, Tèmít\dóp\dé Gbóláhàn +1 more
core +1 more source

