Results 111 to 120 of about 35,022 (298)
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto +13 more
wiley +1 more source
Combination of thiazide and loop diuretics for the treatment of acute heart failure
Acute heart failure (AHF) is a serious condition with a high mortality rate. It is considered as the most common cause of unplanned hospitalizations in the elderly population. In 90% of all cases AHF presents with congestive symptoms, thus mostly treated
Krisztina Fekete +2 more
doaj +1 more source
KEY POINTS AND PRACTICAL RECOMMENDATIONS: • Although chlorthalidone and hydrochlorothiazide are structurally similar, they are very different pharmacokinetically, with chlorthalidone having both an extremely long half-life (approximately 40 to 60 hours) and a large volume of distribution, with gradual elimination from the plasma compartment by tubular
Domenic A, Sica +3 more
openaire +2 more sources
Sodium chloride transport of normal and dietary enlarged rat cecum in vitro [PDF]
Sodium chloride transport across isolated cecum mucosa was investigated in normal rats and rats with adaptive cecum growth induced by dietary polyethylene glycol (PEG). The normal cecum absorbed CI in excess of Na with a small short-circuit current (Isc).
Loeschke, Klaus +2 more
core +1 more source
This study employs an AI‐driven multidisciplinary approach to increase our understanding of the toxicological effects of sublethal concentrations of carlina oxide on Prostephanus truncatus. Sublethal exposure to the carlina oxide induced changes in motor patterns and thigmotaxis, highlighting its potential role in integrated pest management strategies.
Anita Casadei +9 more
wiley +1 more source
Can we improve the treatment of congestion in heart failure? [PDF]
INTRODUCTION: Dyspnoea and peripheral oedema, caused by fluid redistribution to the lungs and/or by fluid overload, are the main causes of hospitalization in patients with heart failure and are associated with poor outcomes.
Bettari L +7 more
core +1 more source
Long‐term remission in gout: Challenges and future opportunities
Prolonged hyperuricemia is a major risk factor for gout, which is now regarded as a curable disease. Awareness of the various factors that can trigger gout flares is essential for their prevention. An important determinant of treatment decisions and long‐term follow‐up is the quality of the clinician–patient relationship. The “treat‐to‐target” approach
Patapong Towiwat, Zhanguo Li
wiley +1 more source
Torasemide – loop diuretic with specific effects
A loop diuretic torasemide is characterized by high bioavailability and prolonged action, explaining some beneficial pharmacodynamic features of the medication.
V. M. Gorbunov, R. G. Oganov
doaj
Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley +1 more source
Reduced efficacy of oral diuretics in the treatment of congestive heart failure (CHF) can be secondary to reduced enteral drug absorption. The aim of this study was to determine the efficacy of subcutaneous (SC) furosemide administration to control the ...
Sergio F. Lombardo +2 more
doaj +1 more source

