Results 51 to 60 of about 35,022 (298)

Diuretic Resistance in Cardio-Nephrology: Role of Pharmacokinetics, Hypochloremia, and Kidney Remodeling

Kidney & Blood Pressure Research, 2019
Background: Diuretic resistance is among the most challenging problems that the cardio-nephrologist must address in daily clinical practice, with a considerable burden on hospital admissions and health care costs.
Cristina Masella, Davide Viggiano, Ida Molfino, Miriam Zacchia, Giovanna Capolongo, Pietro Anastasio, Mariadelina Simeoni   +6 more
doaj   +1 more source

Enteral Sodium Chloride Supplementation and Fluid Balance in Children Receiving Diuretics

Children, 2022
The use of sodium chloride (NaCl) supplementation in children being prescribed diuretics is controversial due to concerns that supplementation could lead to fluid retention.
Laura Ortmann, Teri J. Mauch, Jean Ballweg   +2 more
doaj   +1 more source

Medical treatment of ascites in cirrhosis [PDF]

, 1993
Medical treatment of cirrhotic ascites is essentially supportive, dictated by the patient's discomfort, impaired cardiovascular or respiratory function and potential for infection. Treatment of ‘simple’ ascites (moderate fluid accumulation, serum albumin
Alexander L. Gerbes, Bernardi, Bichet, Bosch, Broekhuysen, Caramelo, Conn, DiBona, Epstein, Faloon, Fogel, Fuller, Ganger, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Ginès, Gregory, Guarner, Henriksen, Hoermann, Jüngst, Karnad, Keppler, Laffi, Lenz, Levy, Moore, Perez-Ayuso, Petrillo, Pockros, Ring-Larsen, Schrier, Schölmerich, Shear, Sherlock   +41 more
core   +1 more source

Pharmacogenetics of loop diuretics

Clinical Pharmacology & Therapeutics, 2004
Objective Genetic variability in pharmacokinetics and pharmacodynamics of diuretics is incompletely studied. We compared the extent of variability in different loop diuretics and determined to what extent this is influenced by polymorphisms in candidate genes. Methods Single oral doses of bumetanide 2 mg, furosemide 80 mg and torasemide 10
Vormfelde, Stefan Viktor, Zirk, A., Westermann, J., Torn, M., Tuchen, F., Toliat, Mohammad Reza, Brockmoeller, Juergen   +6 more
openaire   +2 more sources

Bumetanide: Potent New “Loop” Diuretic [PDF]

BMJ, 1972
Bumetanide, a pharmacologically new diuretic, was evaluated in 27 subjects. Its onset of action was within 30 minutes with a peak at 90 minutes and a total duration of action of about 270 minutes. In a controlled study in oedematous patients it was equipotent with frusemide at one-fortieth the molar dosage and did not differ from frusemide with regard ...
M J, Asbury, P B, Gatenby, S, O'Sullivan, E, Bourke   +3 more
openaire   +2 more sources

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

The independent association between altered renal arterial resistance and loop diuretic dose in chronic heart failure outpatients

International Journal of Cardiology: Heart & Vasculature, 2015
Background: In chronic heart failure (CHF) patients there is a wide variability in the minimal effective diuretic dose. The aim of this study is to evaluate whether renal resistance index (RRI) is associated to baseline diuretic dose and the changes at ...
Massimo Iacoviello, Annalisa Doronzo, Valeria Paradies, Valeria Antoncecchi, Francesco Monitillo, Gaetano Citarelli, Marta Leone, Agata Puzzovivo, Loreto Gesualdo, Marco Matteo Ciccone   +9 more
doaj   +1 more source

Vascular effects of loop diuretics [PDF]

Cardiovascular Research, 1996
Although it is generally believed that the beneficial effect of loop diuretics is the result of a rapid increase in diuresis, substantial evidence, from a large number of in vitro and in vivo experiments, has accumulated showing that administration of furosemide causes direct vascular effects, which probably contribute to its acute clinical effects ...
Dormans, T.P.J., Pickkers, P., Russel, F.G.M., Smits, P.   +3 more
openaire   +4 more sources

NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells [PDF]

, 1986
Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or
Bauer, C., Brown, C. D., Kurtz, Armin, Pfeilschifter, J.   +3 more
core   +1 more source