Loop diuretics in adult intensive care patients with fluid overload: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis [PDF]
Annals of Intensive Care, 2022 Background Fluid overload is a risk factor for organ dysfunction and death in intensive care unit (ICU) patients, but no guidelines exist for its management.
Sine Wichmann +8 more
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Less loop diuretic use in patients on sacubitril/valsartan undergoing remote pulmonary artery pressure monitoring [PDF]
ESC Heart Failure, 2022 Aims Control of pulmonary pressures monitored remotely reduced heart failure hospitalizations mainly by lowering filling pressures through the use of loop diuretics.
Michael Böhm +17 more
doaj +2 more sources
Systematic Review and Meta-Analysis of the Effect of Loop Diuretics on Antibiotic Pharmacokinetics [PDF]
Pharmaceutics, 2023 Loop diuretics and antibiotics are commonly co-prescribed across many clinical care settings. Loop diuretics may alter antibiotic pharmacokinetics (PK) via several potential drug interactions.
David A. Kerling +6 more
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Loop diuretics association with Alzheimer’s disease risk [PDF]
Frontiers in Aging, 2023 Objectives: To investigate whether exposure history to two common loop diuretics, bumetanide and furosemide, affects the risk of developing Alzheimer’s disease (AD) after accounting for socioeconomic status and congestive heart failure.Methods ...
Anna Graber-Naidich +7 more
doaj +2 more sources
Loop Diuretics and Sarcopenia: A Potential Association [PDF]
Muscles, 2023 Background: Loop diuretics (LDs) are used to treat various health conditions including heart failure (HF), liver cirrhosis, and chronic kidney disease (CKD).
Nikolaos D. Karakousis +1 more
doaj +2 more sources
Drug–drug interaction signals between loop diuretics and teicoplanin during acute kidney injury evaluated using Japanese spontaneous adverse drug event reports [PDF]
Scientific Reports, 2023 Teicoplanin can cause acute kidney injury, but little is known about the risk of acute kidney injury when teicoplanin is co-administered with loop diuretics (a powerful diuresis), which can alter renal hemodynamics and glomerular filtration rate.
Toshinori Hirai +5 more
doaj +2 more sources
A retrospective study of 14 dogs with advanced heart failure treated with loop diuretics and hydrochlorothiazide [PDF]
Open Veterinary Journal, 2021 Background: The use of thiazide diuretics is recommended in the American College of Veterinary Internal Medicine guidelines for advanced heart failure due to mitral insufficiency (MI) in dogs.
Koji Iwanaga +2 more
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Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis [PDF]
Journal of Pharmaceutical Health Care and SciencesBackground We examined whether denosumab-induced hypocalcaemia is evident in osteoporosis when given loop diuretics that promote urinary calcium excretion.
Toshinori Hirai +7 more
doaj +2 more sources
Loop diuretics have anxiolytic effects in rat models of conditioned anxiety. [PDF]
PLoS ONE, 2012 A number of antiepileptic medications that modulate GABA(A) mediated synaptic transmission are anxiolytic. The loop diuretics furosemide (Lasix) and bumetanide (Bumex) are thought to have antiepileptic properties.
Andrew D Krystal +2 more
doaj +3 more sources
Therapeutic roles of thiazides and loop diuretics in blood pressure control and renal protection against chronic kidney disease [PDF]
Clinical Hypertension, 2023 Fluid overload secondary to loss of functional nephron mass can elevate blood pressure, which is characteristic of hypertension shown in chronic kidney disease (CKD).
Wonji Jo, Eun Sil Koh, Sungjin Chung
doaj +2 more sources