Loop diuretics association with Alzheimer’s disease risk [PDF]
Objectives: To investigate whether exposure history to two common loop diuretics, bumetanide and furosemide, affects the risk of developing Alzheimer’s disease (AD) after accounting for socioeconomic status and congestive heart failure.Methods ...
Anna Graber-Naidich +7 more
doaj +2 more sources
Continuous Versus Intermittent Loop Diuretics Step‐by‐Step Protocol in Acute Heart Failure (DIUR‐AHF): A Propensity‐Matched Analysis [PDF]
Background Loop diuretics are used to solve congestion in acute heart failure. However, a clear indication about the best infusion modality, dose, and duration of the treatment has not yet been established.
Gaetano Ruocco +16 more
doaj +2 more sources
Drug–drug interaction signals between loop diuretics and teicoplanin during acute kidney injury evaluated using Japanese spontaneous adverse drug event reports [PDF]
Teicoplanin can cause acute kidney injury, but little is known about the risk of acute kidney injury when teicoplanin is co-administered with loop diuretics (a powerful diuresis), which can alter renal hemodynamics and glomerular filtration rate.
Toshinori Hirai +5 more
doaj +2 more sources
Loop diuretics have anxiolytic effects in rat models of conditioned anxiety. [PDF]
A number of antiepileptic medications that modulate GABA(A) mediated synaptic transmission are anxiolytic. The loop diuretics furosemide (Lasix) and bumetanide (Bumex) are thought to have antiepileptic properties.
Andrew D Krystal +2 more
doaj +3 more sources
Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis [PDF]
Background We examined whether denosumab-induced hypocalcaemia is evident in osteoporosis when given loop diuretics that promote urinary calcium excretion.
Toshinori Hirai +7 more
doaj +2 more sources
Ototoxic effects and mechanisms of loop diuretics
Over the past two decades considerable progress has been made in understanding the ototoxic effects and mechanisms underlying loop diuretics. As typical representative of loop diuretics ethacrynic acid or furosemide only induces temporary hearing loss ...
Dalian Ding +8 more
doaj +2 more sources
Combination of SGLT2 Inhibitors and Loop Diuretics in the Treatment of Heart Failure. [PDF]
Background: Administration of SGLT2 inhibitors leads to a reduction in the dosage of loop diuretics in heart failure (HF) patients; however, it is unclear in what patients the dosage can be reduced. We investigated the factors related to the reduction in
Murakami Y +3 more
europepmc +2 more sources
Combination of Loop Diuretics With Thiazide-Type Diuretics in Heart Failure
Volume overload is an important clinical target in heart failure management, typically addressed using loop diuretics. An important and challenging subset of heart failure patients exhibit fluid overload despite significant doses of loop diuretics.
Jacob C Jentzer, Tracy A Dewald
exaly +2 more sources
Impact of Loop Diuretics on Long-Term Kidney Outcome: A Post Hoc Analysis of the STOP-Angiotensin-Converting Enzyme Inhibitor Trial. [PDF]
Background: In the STOP-ACEi trial, patients with advanced CKD were randomised to continue or stop renin–angiotensin system inhibitors (RASi) and showed no difference in kidney outcomes. This post-hoc analysis investigates interactions with loop diuretic
Bhandari S +4 more
europepmc +4 more sources
Renal safety and survival among acutely ill hospitalized patients treated by blockers of the Renin-Angiotensin axis or loop diuretics: a single-center retrospective analysis [PDF]
Background Concern exists regarding the renal safety of blocking the renin-angiotensin system (RAS) during acute illness, especially in the presence of volume depletion and hemodynamic instability.Methods We explored the impact of loop diuretics and RAS ...
May Assaly +4 more
doaj +2 more sources

