Results 1 to 10 of about 8,432 (181)
Olfactomedin 4 as a novel loop of Henle‐specific acute kidney injury biomarker [PDF]
Physiological Reports, 2022 Acute kidney injury (AKI) is associated with morbidity and mortality. Urinary biomarkers may disentangle its clinical heterogeneity. Olfactomedin 4 (OLFM4) is a secreted glycoprotein expressed in stressed neutrophils and epithelial cells. In septic mice,
Denise C. Hasson +7 more
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Thick ascending limb of the loop of Henle. [PDF]
Clin J Am Soc Nephrol, 2014 The thick ascending limb occupies a central anatomic and functional position in human renal physiology, with critical roles in the defense of the extracellular fluid volume, the urinary concentrating mechanism, calcium and magnesium homeostasis, bicarbonate and ammonium homeostasis, and urinary protein composition.
Mount DB.
europepmc +4 more sources
Signal transduction in a compliant short loop of Henle. [PDF]
Int J Numer Method Biomed Eng, 2012 SUMMARYTo study the transformation of fluctuations in filtration rate into tubular fluid chloride concentration oscillations alongside the macula densa, we have developed a mathematical model for tubuloglomerular feedback (TGF) signal transduction along the pars recta, the descending limb, and the thick ascending limb (TAL) of a short‐looped nephron ...
Layton AT, Pham P, Ryu H.
europepmc +5 more sources
A Rare Case of Bartter Syndrome Type 3 Diagnosed in Elderly Age [PDF]
Case Reports in EndocrinologyBartter syndrome (BS) type 3 typically presents in childhood and is caused by defects in NaCl transporters of the thick ascending limb of the loop of Henle.
Tsuyoshi Okura +5 more
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Axial nephron fate switching demonstrates a plastic system tunable on demand [PDF]
Nature CommunicationsThe human nephron is a highly patterned tubular structure that develops specialized cells to regulate bodily fluid homeostasis, blood pressure, and urine secretion throughout life. Approximately 1 million nephrons form in each kidney during embryonic and
MaryAnne A. Achieng +7 more
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Hereditary kidney diseases associated with hypomagnesemia [PDF]
Kidney Research and Clinical Practice, 2021 In the kidney, a set of proteins expressed in the epithelial cells of the thick ascending loop of Henle and the distal convoluted tubule directly or indirectly play important roles in the regulation of serum magnesium levels.
Felix Claverie-Martin +2 more
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As The River Flows: A Case Report of Post Obstructive Diuresis [PDF]
BMC NephrologyBackground Post obstructive diuresis (PObD) is a medical complication that occurs after a period of urinary obstruction. It is defined as a prolonged production of urine of at least 200 cc/hour for two consecutive hours or over 3 L of urine production ...
Evan Finger, Andrew Moses
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Antibiotics, 2021 Aminoglycoside or colistin therapy may alter the renal tubular function without decreasing the glomerular filtration rate. This association has never been extensively investigated.
Martin Scoglio +10 more
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Neonatal Bartter syndrome: A case report from Northern India
Український Журнал Нефрології та Діалізу, 2021 . Bartter Syndrome is a rare genetic disorder affecting the renal tubular system causing a decreased absorption of sodium and chloride in the thick ascending limb of the Henle loop. Most children present in infancy with complaints of polyuria, polydipsia,
Astitva Singh +4 more
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Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney. [PDF]
PLoS ONE, 2016 The kidney displays specialized regions devoted to filtration, selective reabsorption, and electrolyte and metabolite trafficking. The polarized membrane pumps, channels, and transporters responsible for these functions have been exhaustively studied ...
Michael C Stankewich +4 more
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