A Case of Adult onset Bartter Syndrome with Nephrocalcinosis [PDF]
Bartter syndrome is a renal tubular defect in electrolyte transport characterized by hypokalemia, metabolic alkalosis, hyperreninemia, hyperaldosteronism, normal blood pressure, and other clinical symptoms.
Min Gyu Park +5 more
doaj +1 more source
Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney [PDF]
Tamm-Horsfall protein (THP), also known as uromodulin, is a kidney-specific protein produced by cells of the thick ascending limb of the loop of Henle. Although predominantly secreted apically into the urine, where it becomes highly polymerized, THP is ...
Dagher, Pierre C. +12 more
core +1 more source
Renal magnesium handling: New insights in understanding old problems [PDF]
Many sharp-eyed readers have pointed out to us that in the photo next to the article about yams in Ghana (Spore 87, June 2000, page 8), the woman had put all her cassava in one basket, and not the yams she planned to use. Point taken.
Gary A. Quamme +168 more
core +1 more source
Background. Described more than half a century ago, the countercurrent multiplication mechanism in the loop of Henle remains hypothetical; it suggests that tubular flow is significantly influenced by physicochemical processes that have yet to be ...
A. S. Tatevosyan +5 more
doaj +1 more source
TGR5 expression in normal kidney and renal neoplasms
Background The G protein-coupled bile acid receptor (TGR5) is a cell surface receptor which induces the production of intracellular cAMP and promotes epithelial-mesenchymal transition in gastric cancer cell lines.
Chaohui Lisa Zhao +4 more
doaj +1 more source
Autosomal dominant hypocalcemia with Bartter syndrome due to a novel activating mutation of calcium sensing receptor, Y829C [PDF]
The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium resorption in kidney.
Keun Hee Choi +3 more
doaj +1 more source
Advances in the correlation of uromodulin and UMOD gene with chronic kidney disease [PDF]
Uromodulin, also known as Tamm-Horsfal protein, is the most abundant protein in normal urine. It is exclusively secreted by renal tubular epithelial cells in thick ascending limb (TAL) of the Henle loop.
YOU Rui-lian, XU Lu-bin, CHEN Li-meng
doaj
Single-cell transcriptome analysis of a rat model of bilateral renal ischemia-reperfusion injury
Ischemia-reperfusion injury (IRI) causes massive tissue damage. Renal IRI is the most common type of acute renal injury, and the defects caused by it may progress to chronic kidney disease (CKD).
Ayumu Taniguchi +12 more
doaj +1 more source
Potassium secretion by the descending limb or pars recta of the juxtamedullary nephron in vivo [PDF]
Potassium secretion by the descending limb or pars recta of the juxtamedullary nephron in vivo. Potassium reabsorption by the juxtamedullary nephron up to the hairpin turn was studied by the micropuncture technique in the exposed renal papilla of rats ...
Baas, Frank +4 more
core +2 more sources
Uromodulin — Biological Significance and Prospects for Clinical Use
Uromodulin is a unique protein produced in the kidneys by epithelial cells of the ascending thick portion of the loop of Henle. It implements physiological mechanisms not only at the tubular level, but also participates in the coordination of general ...
E. S. Levitskaya +2 more
doaj +1 more source

