Results 51 to 60 of about 173,316,258 (215)
Environmental Toxicology, EarlyView.ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida +7 more
wiley +1 more source
Henle, Gertude -- 1955 -- Correspondence, Individual -- text, 1955-09-08
, 1955 Sabin Collection Fair Use PolicyLetter from Henle, Gertrude to Sabin, Albert B.
Henle, Gertrude, 1912-
core +1 more source
Cell Proliferation, EarlyView.Renal IRI induces tubular EMT and fibrosis. CD11c+AREG+ DCs mediate the process via AREG‐EGFR axis, serving as promising therapeutic targets. ABSTRACT Renal ischemia–reperfusion injury (RIRI) is a major cause of acute tubular damage and a key driver of maladaptive repair and fibrosis.
Xin Luo +14 more
wiley +1 more source
Thick ascending limb of Henle's loop
Kidney International, 1982 Thick ascending limbs of Henle's loop have at least three major roles: (1) They reabsorb sodium chloride which dilutes the urine. (2) The reabsorption of sodium chloride also produces concentration gradients that drive the countercurrent multiplier system in the medulla and medullary rays and thus concentrates the urine. (3) They reabsorb large amounts
openaire +2 more sources
Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice
Cell Reports, 2016 The kidney has a tremendous capacity to regenerate following injury, but factors that govern this response are still largely unknown. We isolated cells from mouse kidneys with high proliferative and multi-lineage differentiation capacity.
Hyun Mi Kang +5 more
doaj +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Survodutide is a novel long‐acting dual glucagon (GCGR)/glucagon‐like peptide‐1 (GLP‐1R) receptor agonist currently in phase‐3 clinical development for the treatment of people living with obesity and metabolic dysfunction‐associated steatohepatitis.
Alexander Hamilton +11 more
wiley +1 more source
Insect Conservation and Diversity, EarlyView.Troglobites strongly shape community responses to environmental gradients, weakening patterns when excluded from analysis. High beta diversity dominated by species replacement, driven by distance from entrance and microclimatic factors. Resource availability and microclimate stability are key to maintaining this subterranean biodiversity hotspot ...
Roberta Fernanda Ventura Cerqueira +4 more
wiley +1 more source
Bicarbonate transport along the loop of Henle. II. Effects of Acid-base, Dietary, and Neurohumoral determinants. [PDF]
, 1994 The loop of Henle contributes to renal acidification by reabsorbing about 15% of filtered bicarbonate. To study the effects on loop of Henle bicarbonate transport (JHCO3) of acid-base disturbances and of several factors known to modulate sodium transport,
R. Unwin +13 more
core +2 more sources
Bartter syndrome-like phenotype in a patient with diabetes: a case report
Journal of Medical Case Reports, 2018 Background Bartter’s syndrome is a rare genetic tubulopathy affecting the loop of Henle leading to salt wasting. It is commonly seen in utero or in early neonatal period.
Chamara Dalugama +2 more
doaj +1 more source
Renal glycogen handling in diabetes: A narrative review of diabetic kidney disease pathogenesis
Journal of Diabetes Investigation, EarlyView.ABSTRACT Kidney disease is a major microvascular complication of diabetes, affecting approximately 40% of individuals with diabetes, and is a leading cause of end‐stage renal disease. Besides the functional consequences of hyperglycemia; hemodynamic alterations are well understood.
Deenadhayalan Ashok +3 more
wiley +1 more source