Results 11 to 20 of about 8,432 (181)
Physiology and pathophysiology of ClC-K/barttin channels
ClC-K channels form a subgroup of anion channels within the ClC family of anion transport proteins. They are expressed predominantly in the kidney and in the inner ear, and are necessary for NaCl resorption in the loop of Henle and for K+ secretion by ...
Christoph eFahlke, Martin eFischer
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Loop tubulopathies: Bartter’s syndrome
The authors provide a review of current clinical guidelines regarding medical care provided to children with Bartter’s syndrome — impaired renal tubular function (loop of Henle) with the development of hypokalemia, hypochloremia, metabolic alkalosis and ...
Alexander A. Baranov +15 more
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New Strategies for Volume Control in Patients with Diabetes Mellitus, a Narrative Review
Sodium is reabsorbed all along the renal tubules. The positive impacts of sodium-glucose cotransporter-2 inhibitors (SGLT2i), angiotensin receptor neprilysin inhibitor (ARNI) and mineralocorticoid receptor antagonists (MRA) on hard renal and/or cardiac ...
Alexandre O. Gérard +7 more
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Role of Prox1 in the Transforming Ascending Thin Limb of Henle's Loop during Mouse Kidney Development. [PDF]
The homeobox transcription factor Prox1 is critical to the development of many embryonic organs and tissues, although current understanding of its expression in the developing renal medulla is limited.
Yu-Mi Kim +7 more
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Function of thin loops of Henle
The existence of a steep osmotic gradient in the renal medullary interstitium is the most critical in the formation of concentrated urine [1]. The architectural organization of the renal tubules and blood vessels in the medulla constitutes counterflow systems which are essential for both generating and maintaining high osmotic pressure of the renal ...
Imai, Masashi +2 more
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Natural Ventilation with Heat Recovery: A Biomimetic Concept
In temperate countries, heat recovery is often desirable through mechanical ventilation with heat recovery (MVHR). Drawbacks of MVHR include use of electric power and complex ducting, while alternative passive heat recovery systems in the form of roof or
Zulfikar A. Adamu, Andrew D.F. Price
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Hypercalcemia is often seen in patients with malignancies, and in the past treatment for this has traditionally included loop diuretics. Clinically, patients with hypercalcemia frequently present with polyuria and volume contraction which may be further ...
Ira W. Reiser +3 more
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Unusual case of failure to thrive: Type III Bartter syndrome
Bartter syndrome Type III is a rare autosomal recessive disorder resulting from an inherited defect in the thick ascending limb of the loop of henle of the nephrons in kidney.
Sumit Agrawal +3 more
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An Adult Case of Bartter Syndrome Type III Presenting with Proteinuria [PDF]
Bartter syndrome (BS) I–IV is a rare autosomal recessive disorder affecting salt reabsorption in the thick ascending limb of the loop of Henle. This report highlights clinicopathological findings and genetic studies of classic BS in a 22-year-old female ...
Eun Jung Cha +3 more
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Review on analytical methods for determination of furosemide [PDF]
Furosemide (FRS) belongs to loop diuretics. The drug is prescribed for the treatment of hypertension and heart failure. FRS inhibits the reabsorption of electrolytes mainly in the thick ascending limb of the loop of Henle and also in the distal renal ...
Mona Abo Zaid +4 more
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