Results 111 to 120 of about 6,563,661 (318)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Loop spaces and homotopy operations
, 1997 The question of whether a given H-space X is, up to homotopy, a loop space has been studied from a variety of viewpoints. Here we address this question from the aspect of homotopy operations, in the classical sense of operations on homotopy groups ...
Blanc, David
core +1 more source
Finite loop spaces are manifolds
Acta Mathematica, 2004 The purpose of this work is to show the following result: Theorem: Let \(B\) be a CW-complex and denote by \(X\) the loops on \(B\), \(\Omega B\). If \(H_*(X)=\bigoplus _i H_i(X)\) is a finitely generated abelian group, then \(X\) is homotopy equivalent to a compact, smooth parallelizable manifold.
Bauer, T. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Asymptotic behavior of divergences and Cameron-Martin theorem on loop spaces
, 2004 We first prove the L^p-convergence (p\geq 1) and a Fernique-type exponential integrability of divergence functionals for all Cameron-Martin vector fields with respect to the pinned Wiener measure on loop spaces over a compact Riemannian manifold.
Li, Xiang Dong
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Ribbon braids and related operads [PDF]
, 2001 This thesis consists of two parts, both being concerned with operads related to the ribbon braid groups. In the first part, we define a notion of semidirect product for operads and use it to study the framed $n$-discs operad (the semidirect product $f ...
Wahl, N.
core
On simplicial loops and H-spaces
Topology and its Applications, 2001 Let \(X\) be a connected \(H\)-space and \(A\) a CW-complex. Then, according to I. M. James, the set \([A,X]\) of based homotopy classes has the structure of an algebraic loop, induced by the \(H\)-space structure of \(X\). The author shows that this is a consequence of a deeper result: Any minimal Kan subset \(M_\bullet\) of the singular set \(S_ ...
openaire +2 more sources