Results 41 to 50 of about 1,262,827 (293)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Are Loosely Coupled Organizations Resilient to Crises? Five French Higher Education Institutions Facing Covid

open access: yesJournal of Organizational Sociology
Most authors conclude that loose coupling plays a positive role during a crisis but very few, if any, empirically examine what concretely happens when loosely coupled organizations – that is, organizations with a high number of loosely coupled activities
Mignot-Gérard Stéphanie   +2 more
doaj   +1 more source

DESIGN OF A RESONANT SOFT SWITCHING POWER SUPPLY FOR STABILIZED DC IMPULSE DELIVERY [PDF]

open access: yes, 2012
This thesis addresses the issues involved in the design and construction of a multiphase resonant switching power supply for delivery of a high voltage, high current stabilized DC impulse.
Seltzman, Andrew
core  

Loosely-coupled Service I/O mechanism.

open access: yes, 2015
Loosely-coupled Service I/O mechanism.
Matthew Zhan (698896)   +6 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

A groupware design framework for loosely coupled workgroups

open access: yes, 2005
Loosely coupled workgroups – where workers are autonomous and weakly interdependent – are common in the real world. They have patterns of work and collaboration that distinguish them from other types of groups, and groupware systems that are designed to ...
Gutwin, Carl, Pinelle, David
core   +2 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Toward loosely coupled programming on petascale systems [PDF]

open access: yes2008 SC - International Conference for High Performance Computing, Networking, Storage and Analysis, 2008
IEEE/ACM International Conference for High Performance Computing, Networking, Storage and Analysis (SuperComputing/SC ...
Ioan Raicu   +6 more
openaire   +3 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Improving groupware design for loosely coupled groups [PDF]

open access: yes, 2004
Loosely coupled workgroups are common in the real world, and workers in these groups are autonomous and weakly interdependent. They have patterns of work and collaboration that distinguish them from other types of groups, and groupware systems that are ...
Pinelle, David
core  

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