Results 131 to 140 of about 23,058 (301)

Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.

open access: yesPLoS Medicine, 2007
BackgroundLoperamide is widely used in adults for acute diarrhea. However, its use in children has been discouraged by the World Health Organization and the American Academy of Pediatrics owing to concerns over safety and efficacy in young children ...
Su-Ting T Li   +2 more
doaj   +1 more source

Acquired Multiple Acyl‐Coenzyme A Dehydrogenase Deficiency Associated With Sertraline in Sweden—A Nationwide Population‐Based Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
Multiple acyl‐coenzyme A dehydrogenase deficiency‐like disease has recently been described as a rare adverse effect of sertraline. We performed a nationwide population‐based retrospective study in Sweden (2014–2024) including 40 patients, corresponding to an incidence of 1.24 per 100,000 treated individuals per year.
Sofie Sunebo   +9 more
wiley   +1 more source

Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana) [PDF]

open access: yes, 2011
This study screened the antidiarrhoeal, antimicrobial and cytotoxic effects of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). The extract was tested against castor oil-induced diarrhoea in a model of albino rats and showed significant ...
A. Islam   +5 more
core   +3 more sources

Comparison of Human and Canine P‐Glycoprotein Substrates at R, P, and H Binding Sites

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 2, Page 120-130, March 2026.
ABSTRACT P‐glycoprotein (P‐gp) greatly impacts substrate drug disposition, so much so that regulatory agencies recommend ascertaining the P‐gp status of active pharmaceutical ingredients (APIs) intended for human use. Arguably, the P‐gp status of drugs intended for canine patients is equally, if not more, important.
Neal S. Burke, Katrina L. Mealey
wiley   +1 more source

Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide

open access: yesEndocrine Regulations, 2018
Objective. This study investigated whether the metformin (Met)-induced enhanced intestinal uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) is reduced by loperamide, a long-acting anti-diarrheal agent. Methods.
Nobashi Tomomi   +8 more
doaj   +1 more source

Coronary artery spasm after ingestion of Imodium (loperamide) in a 14-year-old boy

open access: yesAnnals of Pediatric Cardiology, 2016
We report a 14-year-old boy who presented with acute chest pain, following the ingestion of loperamide for acute diarrhea. Twelve lead electrocardiogram (ECG) showed evidence of acute ischemia indicating acute coronary artery spasm.
Tayyaba Sehar, Masood Sadiq
doaj   +1 more source

Effective Management of Flatulence [PDF]

open access: yes, 2009
Probiotics and rifaximin (Xifaxan) have been shown to reduce total number of flatus episodes and associated discomfort. (Strength of Recommendation [SOR]: B, based on small randomized controlled trials [RCTs]).
Bailey, Justin, Carter, Nakia Joyce
core  

Antisecretory and analgesic activities of Terminalia bellerica [PDF]

open access: yes, 2010
This study describes the antisecretory and analgesic activities of the crude extract of Terminalia bellerica (Tb.Cr). T. bellerica extract inhibited the castor oil-induced intestinal fluid secretion in mice at the dose range of 300 - 1000 mg/kg.
Gilani, Anwar Hassan, Khan, Arif-ullah
core   +1 more source

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