Results 251 to 260 of about 23,058 (301)

Lychee Pulp-Derived Dietary Fiber-Bound Phenolic Complex Upregulates the SCFAs-GPRs-ENS Pathway and Aquaporins in Loperamide-Induced Constipated Mice by Reshaping Gut Microbiome.

Journal of Agricultural and Food Chemistry, 2023
This study aimed to investigate the effects of the lychee pulp-derived dietary fiber-bound phenolic complex (DF-BPC) on a murine model of loperamide-induced constipation and its molecular mechanism associated with gut microbiota modification.
Lihong Dong, Zhuohui Xu, Guitao Huang, Ruifen Zhang, Mei Deng, F. Huang, Dongxiao Su   +6 more
semanticscholar   +1 more source

Chitosan oligosaccharides attenuate loperamide-induced constipation through regulation of gut microbiota in mice.

Carbohydrate Polymers, 2021
This study was designed to explore the improvement of chitosan oligosaccharides (COS) on constipation through regulation of gut microbiota. Here, we proved that COS treatment profoundly boosted intestinal motility, restrained inflammatory responses ...
Xiaoyu Zhang, Huabing Yang, Junping Zheng, Nan-hui Jiang, Guangjun Sun, Xinkun Bao, Aizhen Lin, Hongtao Liu   +7 more
semanticscholar   +1 more source

Racecadotril versus Loperamide in acute radiation enteritis: a randomized, double-blind, phase 3, non-inferiority trial.

International Journal of Radiation Oncology, Biology, Physics, 2023
INTRODUCTION There is currently no gold standard available for the management of acute radiation enteritis. We compared the efficacy and safety of Racecadotril an antihypersecretory drug versus Loperamide an anti-motility agent in acute radiation ...
Dr P.B. Abhijith, Dr Shyama Prem Sudha, Dr Pazhanivel Mohan, Dr Ninad Harish Patil, Dr K.A. Asif Rahman, Dr Bhargav Shreeram Gundapuneedi, D. Harish   +6 more
semanticscholar   +1 more source

Identification of a novel adjuvant loperamide that enhances the antibacterial activity of colistin against MCR-1-positive pathogens in vitro/vivo.

Letters in Applied Microbiology, 2023
Severe infection with MDR Enterobacterales caused by the plasmid-induced colistin resistance gene MCR-1 is a serious public health challenge. In this case, it is necessary and pressing to find a treatment to overcome antibiotic resistance.
Yuqing Zhang, Liming Shi, Lu Lv, Yan Zhang, Huiping Chen   +4 more
semanticscholar   +1 more source

Loperamide Cardiac Toxicity - Pathophysiology, Presentation and Management.

Canadian Journal of Cardiology, 2022
Loperamide is a non-prescription medication commonly used to treat diarrhea. Although it is an opioid, it is very poorly absorbed and well tolerated, with no systemic toxicity at standard doses.
Peter E. Wu, D. Juurlink
semanticscholar   +1 more source

Bamboo shavings derived O-acetylated xylan alleviates loperamide-induced constipation in mice.

Carbohydrate Polymers, 2021
BSH-1 is an O-acetylated xylan obtained from bamboo shavings. This study determined the protective effects of BSH-1 against loperamide (Lop)-induced constipation in mice. Mice received BSH-1 by gavage daily for 14 days.
Juqing Huang, Bin Lin, Ying Zhang, Zhenglu Xie, Yi Zheng, Qi Wang, Hang Xiao   +6 more
semanticscholar   +1 more source

The protective effects of yellow tea extract against loperamide-induced constipation in mice.

Food & Function, 2021
Yellow tea, a rare type tea from China, has a rich breadth of functional ingredients and benefits the gastrointestinal tract. However, it is not clear whether the yellow tea extract can alleviate constipation.
Pei Cao, Xiu-ping Li, Ouyang Jian, R. Jiang, Fang-fang Huang, Bei-bei Wen, Xiang-Na Zhang, Jian-an Huang, Zhong-Hua Liu   +8 more
semanticscholar   +1 more source

An Opioid Hiding in Plain Sight: Loperamide-Induced False-Positive Fentanyl and Buprenorphine Immunoassay Results.

The Journal of Applied Laboratory Medicine, 2022
BACKGROUND Loperamide (Imodium®), a commonly used anti-diarrheal, is a mu opioid receptor agonist that, like all opioids, reduces gastrointestinal tract peristalsis. Loperamide is considered to have low abuse potential as it does not produce an analgesic
K. A. Geno, Adina Badea, K. Lynch, P. Jannetto, Jacqueline A. Hubbard, R. D. Nerenz, M. Cervinski   +6 more
semanticscholar   +1 more source

Loperamide Induces Excessive Accumulation of Bile Acids in the Liver of Mice with Different Diets.

Toxicology, 2022
Loperamide is a non-prescription medicine normally used for the treatment of diarrhea. The abuse and misuse of loperamide have been demonstrated to have toxic effects on heart.
Zili Lei, Hedong Rong, Yanhong Yang, Siping Yu, Tianle Zhang, Lei Chen, Ya Nie, Qi Song, Q. Hu, Jiao Guo   +9 more
semanticscholar   +1 more source

Modulation of gut microbiota and intestinal metabolites by lactulose improves loperamide-induced constipation in mice.

European Journal of Pharmaceutical Sciences, 2020
Lactulose is a common laxative and has been widely applied to clinical treatment for constipation. This study aimed to explore the improving effect of lactulose on constipation through the mediation of gut microbiota and intestinal metabolites.
Xiaoyu Zhang, Junping Zheng, Nan-hui Jiang, Guangjun Sun, Xinkun Bao, Mingwang Kong, Xue Cheng, Aizhen Lin, Hongtao Liu   +8 more
semanticscholar   +1 more source