Results 11 to 20 of about 566 (103)

Mapping Organelle Proteins and Protein Complexes in Drosophila melanogaster

, 2016
Many proteins within eukaryotic cells are organized spatially and functionally into membrane bound organelles and complexes. A protein’s location thus provides information about its function. Here, we apply LOPIT, a mass-spectrometry based technique that
Paul Bertone (478638), Kathryn S. Lilley (73966), Denise J. L. Tan (2370559), Alfonso Martinez Arias (198081), Heidi Dvinge (2370562), Andrew Christoforou (2370556)   +5 more
core   +13 more sources

An updated Bioconductor workflow for correlation profiling subcellular proteomics [version 1; peer review: 2 approved] [PDF]

F1000Research
Background Subcellular localisation is a determining factor of protein function. Mass spectrometry-based correlation profiling experiments facilitate the classification of protein subcellular localisation on a proteome-wide scale.
Lisa M Breckels, Laurent Gatto, Thomas Krueger, Kathryn S Lilley, Charlotte Hutchings, Oliver M Crook   +5 more
doaj   +2 more sources

Reduced mitochondria provide an essential function for the cytosolic methionine cycle

Current Biology, 2022
Justyna Zitek, Zoltan Fussy, Sebastian C Treitli   +2 more
exaly   +3 more sources

Localization of Organelle Proteins Using Data-Independent Acquisition (DIA-LOP) [PDF]

Molecular and Cellular Proteomics
Kathryn S Lilley, Charlotte Hutchings, Renata Férêt   +2 more
exaly   +2 more sources

Toxoplasma ceramide synthases: Gene duplication, functional divergence, and roles in parasite fitness

The FASEB Journal, Volume 37, Issue 11, November 2023., 2023
The Toxoplasma “pseudo” ceramide synthase (TgCerS2) defines a novel apicomplexan class of these essential enzymes. Abstract Toxoplasma gondii is an obligate, intracellular apicomplexan protozoan parasite of both humans and animals that can cause fetal damage and abortion and severe disease in the immunosuppressed.
Zisis Koutsogiannis, John G. Mina, Christin A. Albus, Matthijs A. Kol, Joost C. M. Holthuis, Ehmke Pohl, Paul W. Denny   +6 more
wiley   +1 more source

Proximity‐dependent biotinylation approaches to study apicomplexan biology

Molecular Microbiology, Volume 117, Issue 3, Page 553-568, March 2022., 2022
Proximity‐dependent biotinylation (PDB) approaches using PDB enzymes such as BirA* and APEX have emerged as powerful tools for interactome and compartment proteome studies. Here we describe the general properties, principles, and recent improvements of PDB.
Jessica Kimmel, Jessica Kehrer, Friedrich Frischknecht, Tobias Spielmann   +3 more
wiley   +1 more source

Late results of surgical treatment of critical ischemia of the lower extremities after one-staged direct revascularization

Клінічна хірургія, 2021
Objective. To optimize the tactics of surgical treatment in patients, suffering chronic ischemia of the lower extremities with the help of elaboration and introduction of a one-staged direct and indirect revascularization into clinical practice ...
M. M. Lopit, V. І. Rusyn, P. A. Boldizhar, F. V. Gorlenko, O. M. Kochmar   +4 more
doaj   +1 more source

G-Lopit: Grouped Lazy Optimization of Packet Injection Timing in Collective Communication

IEICE Transactions on Information and Systems
Takashi Yokota
exaly   +2 more sources

Quantitative indicators of microcirculation of the skin of the lower extremities

Сучасні медичні технології, 2020
Purpose of the study. To study the quantitative indicators of microcirculation and perfusion of the skin of the lower extremities, taking into account the angiosomal theory.   Materials and methods.
V. I. Rusin, P. O. Boldizhar, F. V. Gorlenko, M. M. Lopit   +3 more
doaj   +1 more source

CambridgeCentreForProteomics/thp-lopit-2021: code and vignette

, 2021
<p>R code and vignette release for the data analysis conducted in the manuscript entitled "Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line" submitted to
Lisa Breckels
core   +1 more source