Results 71 to 80 of about 31,031 (195)

Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency

Epilepsia, EarlyView.
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon, Shuyun Wang, Qinghua Liu, Chunling Chen, Alexander M. Greiner, Abigail M. Marx, Maya Shih, Jack M. Parent, Barry London, Lori L. Isom   +9 more
wiley   +1 more source

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source

Inclusive Team Internships in Sustainability Studies as a Promising Practice for Enhancing Sense of Belonging Among Groups Underrepresented in STEM

New Directions for Higher Education, EarlyView.
ABSTRACT Sense of belonging is regularly cited as a barrier for student entry into science, technology, engineering, and mathematics (STEM) fields. This study of six years of data, collected from 160 undergraduate students who participated in the summer Green Teams Internship Program managed by the PSEG Institute for Sustainability Studies at Montclair
Elizabeth Emery, Hailey Spinks, Matthew Murray, Yasemin Besen‐Cassino, Brian Johnson, Emma Nunez Perez, Iman Cumberbatch, Lora Billings, Nina Goodey, Amy Tuininga   +9 more
wiley   +1 more source

Health System Factors in Head and Neck Cancer Diagnosis: A HEADSpAcE Consortium Qualitative Study in Glasgow and Montevideo

Head &Neck, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney, Iván Lyra González, Mauricio Cuello, Mariél de Aquino Goulart, Alex D. McMahon, Claire Paterson, James McCaul, Maja Popovic, Lorenzo Richiardi, Silvia Lopez de Blanc, Maria Paula Curado, Marta Vilensky, HEADSpAcE Consortium, Elmira Ebrahimi, Apiwat Sangphukieo, Hanla A Park, Valerie Gaborieau, Wolfgang Ahrens, Laia Alemany, Lidia MRB Arantes, Jaroslav Betka, Cristina Canova, David I Conway, Mauricio Cuello, Maria Paula Curado, Ana Carolina de Carvalho, Jose Carlos de Oliviera, Mark Gormley, Maryam Hadji, Claire M Healy, Ivana Holcatova, Luis P Kowalski, Pagona Lagiou, Areti Lagiou, Gary J Macfarlane, Sandra Perdomo, Luis Felipe Ribiero Pinto, Jose Roberto V Podesta, Jerry Polesel, Miranda Pring, Hamideh Rashidian, Ricardo R Gama, Lorenzo Richiardi, Max Robinson, Paula A Rodriguez‐Urrego, Sheila C Soares‐Lima, Nicolas Timpson, Marta Vilensky, Sandra V von Zeidler, Tim Waterboer, Kazem Zendehdel, Ariana Znaor, Paul Brennan, James McKay, Shama Virani, Tom Dudding, Roque Adam, Antonio Agudo, Shaymaa F AlWaheidi, Miquel Angel Pavon, Namrah Anwar, Paola Engelmann Arantes, Lisa Arguello, Yubelly Avello, Lucas Avondet, Ana M Baldión‐Elorza, Camila Batista Daniel, Bianca Beraldi, Barbara Berenstein, Patricia Bernal, Natália Bernardino Rodrigues, Josipa Bilic Zimmermann, Marianna G Botta, Jesús Brenes, Nicole Brenner, Carol Brentisci, Catalina Burtica, María L Cabañas, Erick Cantor, Raiany S Carvalho, Andre L Carvalho, Luigi Chiusa, Priscilia Chopard, Qurratulain Chundriger, Omar Clavero, Isabela Costa, Grant Creaney, Cecilia Cuffini, Tauana C Dias, Evandro Duccini de Souza, Lais C Durant, Alberto Escallón, Gisele Aparecida Fernandes, Béatrice Fervers, Valentina Fiano, Frederico Firme Figueira, Regina Furbino Villefort, Manuela Gangemi, Paolo Garzino‐Demo, Mahin Gholipour, Raul Giglio, Mariel A Goulart, Jéssica Graça Sant'Anna, Marek Grega, Anna Clara Gregório Có, Arnau Guasch, Jose A Hakim, David N Hayes, Marco Homero de Sá Santos, Katrina Hurley, Magalí Insfran, Giuseppe C Iorio, Moghira Iqbaluddin Siddiqui, Jannik Johannsen, Martin Kaňa, Jens Peter Klussmann, Evelio Legal, Jeferson Lenzi, Fernando Luiz Dias, Iván Lyra González, Willene Machado Zorzaneli, Ricardo Mai Rocha, Manel Mañós, Priscila Marinho de Abreu, Maryam Marzban, James McCaul, Alex D. McMahon, Carlos Mena, Elismauro F Mendonça, Laura Mendoza, Lorena Meza, Birgitta Michels, Matinair S Mineiro, Chiara Moccia, Pamela Mongelos, Ana L Montealegre‐Páez, Francisca Morey Cortes, Alvaro Muñoz, Andy Ness, Aline B Neves, Marco Oliva, José Carlos de Oliveira, Hernán Ortiz, José Ortiz, Marta Osorio, Vanessa Ospina, Oliviero Ostellino, Mauricio Palau, Claire Paterson, Sonia Paytubi Casabona, Giancarlo Pecorari, David M Pereira, Olivia Pérol, Shahid Pervez, Alicia Pomata, Maja Popovic, Alisson Poveda, Carol P Prado, Kristina M Prager, Guglielmo Ramieri, Juliana NI Rego, Rui M Reis, Helene Renard, Umberto Ricardi, Giuseppe Riva, Frederic Rodilla, Ingrid Rodriguez, María I Rodríguez, Alastair Ross, Pierre‐Eric Roux, Tazeen Saeed Ali, Pierre Saintigny, Juan J Santivañez, Cristóvam Scapultampo‐Neto, Javier Segovia, Agenor Sena, Ricardo Serrano, Shachi J Sharma, Oliver Siefer, Stephanie Smart, Bruna P Sorroche, Cinthia Sosa, Juliana Souza de Oliveira, Antonella Stura, Steven Thomas, Oscar Torres, Sara Tous, Gonzálo Ucross, Adriana Valenzuela, José Roberto Vasconcelos de Podestá, Alex Whitmarsh, Sylvia Wright, Shaymaa Alwaheidi, Paul Brennan, Shama Virani, Al Ross, David I Conway   +196 more
wiley   +1 more source

PRODUKTIVITAS ANGKUTAN LORI DORONG DI HUTAN JATI

Jurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017
A study on the productivity of lorry transportation in the teak forest was carried out in 1982, at  three forest  Districts. Time study have been conducted for this purpose.
Apul Sianturi
doaj   +1 more source

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

Head &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su, Matheus Sewastjanow‐Silva, Jack Phan, Marc‐Elie Nader, Shaan M. Raza, Franco DeMonte, Paul W. Gidley, Ehab Y. Hanna, Loretta A. Williams   +8 more
wiley   +1 more source

Integrating Immunotherapy Into Head and Neck Surgery: Bridging Tumor Biology to Perioperative Decision‐Making, a Review

Head &Neck, EarlyView.
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley   +1 more source

The use of activated carbon derived from spent coffee grounds as a reusable, sustainable, and effective solution for the removal of butylparaben from water

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Parabens, including butylparaben (BP), are widely used as antimicrobial preservatives in food, cosmetics, and pharmaceuticals, yet are poorly removed by conventional water treatment processes and pose potential risks to aquatic life and human health.
Lorena Maihury Santos Tsubouchi, Diane Scapin, Gideã Taques Tractz, Flávia Aparecida Reitz Cardoso, Lúcio Cardozo‐Filho, Alessandro Francisco Martins, Diógenes Vedoy, Ana Paula Peron, Osvaldo Valarini Junior   +8 more
wiley   +1 more source

Study of polymorphism of Myostatin gene and its association with growth traits in lori sheep

پژوهشهای علوم دامی ایران, 2015
Myostatin gene or growth and differentiation factor-8 inhibits the puberty and development of skeletal muscles and it could change the size of some muscles such as double muscle, if the mutation occurs. One of the most important indigenous sheep in Iran,
Fatemeh Bahramzadeh, Gholamreza Dashab, Masoud Alipana, Mohammad Rokouei, Sadegh Asadollaei   +4 more
doaj  

Unveiling Dental Students’ Baseline Self‐Regulated Learning Skills During an Authentic Diagnostic Reasoning Task

Journal of Dental Education, EarlyView.
ABSTRACT Purpose/Objectives This study aimed to cross‐culturally adapt and gather validity evidence for two instruments—the Self‐Regulated Learning Microanalytic Assessment (SRL‐MA) and the Assessment of Reasoning Tool—Reconstructed (ART‐R)—for assessing dental students' baseline self‐regulated learning (SRL) skills and diagnostic reasoning performance
Lorena Isbej, Dominique Waterval, Arnoldo Riquelme, Claudia Véliz, Ana Andaur, Paulina Freire, Anique B. H. de Bruin   +6 more
wiley   +1 more source