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Results 81 to 90 of about 31,145 (194)

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo +10 more
wiley +1 more source

Frequency of ZFHX3‐Mediated Spinocerebellar Ataxia 4 in a US Undiagnosed Ataxia Cohort

Movement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia 4 (SCA4) is a late‐onset dominant ataxia with neuropathy caused by exonic GGC repeat expansion in the ZFHX3 gene thought to originate from a Swedish founder event. The GC‐rich expansion is highly thermodynamically stable, posing challenges for standard clinical genetic testing methods.
Annie Chen +320 more
wiley +1 more source

Book review: Kostelecky, Sarah R., Townsend, Lori and Hurley, David A. Hopeful visions, practical actions: cultural humility in library work

Information Research: An International Electronic Journal
Kostelecky, Sarah R., Townsend, Lori and Hurley, David A. Hopeful visions, practical actions: cultural humility in library work. London: Facet Publishing, 2023. xxiii, 236 p.
Elena Maceviciute
doaj +2 more sources

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink +5 more
wiley +1 more source

Mortality in an invasive ant does not scale linearly with fipronil exposure

Pest Management Science, EarlyView.
Increasing fipronil concentration did not linearly increase yellow crazy ant mortality when introduced via horizontal transfer; high doses may limit food sharing. Queen mortality was low, and surviving workers were averse to feeding. Abstract Background Controlling eusocial invasive and other pestiferous insects is difficult.
Peter Yeeles, Angela Strain, Lori Lach
wiley +1 more source

Systematic Review and Meta‐Analysis: Plant‐Based Therapy for Irritable Bowel Syndrome

Phytotherapy Research, EarlyView.
ABSTRACT Irritable bowel syndrome (IBS) is a common disorder of brain‐gut interaction that presents with abdominal pain, bloating associated with variable stool consistency. Many IBS patients prefer plant‐based preparations to pharmacological therapy; however, the utility of this approach is not well established.
Anselm Meyer +8 more
wiley +1 more source

Riparian Failure: Damming and Flow Stabilization Exclude Cottonwood Colonization Along a Dryland River

River Research and Applications, EarlyView.
ABSTRACT The Marias River flows from Glacier National Park through northcentral Montana, and into the Missouri River. Annual flows gradually declined from 1902 to 2024 (~3.2%/decade) and the 1952 Tiber Dam and Lake Elwell reservoir were operated to attenuate peak flows and stabilize downstream flows year‐round.
Stewart B. Rood, Lori A. Goater
wiley +1 more source

Artificial intelligence in out‐of‐hospital sleep monitoring: Bridging polysomnography and wearable signals

Sleep Research, EarlyView.
Abstract Polysomnography (PSG), the reference standard for sleep assessment, has limited scalability for large‐scale screening, driving the development of wearable and unobtrusive monitors. However, the physiological signals these devices capture are physiologically correlated with PSG channels but are not completely equivalent.
Jing Yan +5 more
wiley +1 more source

Levodopa and Melanoma: Practical Recommendations for Parkinson's Disease—International Parkinson and Movement Disorder Society Scientific Issues Committee Viewpoint

Movement Disorders Clinical Practice, EarlyView.
Giorgia Sciacca +27 more
wiley +1 more source

Multifunctional Nanodiamond Conjugate With a Tumor‐Specific EGFR‐Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers

Small, EarlyView.
A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre +12 more
wiley +1 more source

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