Results 101 to 110 of about 134,904 (303)

Особенности образов зла в творчестве Дж.Р.Р. Толкина [PDF]

open access: yes, 2014
DISTINCTIVE FEATURES OF NEGATIVE CHARACTERS IN J.R.R. TOLKIEN’S “THE LORD OF THE RINGS”. О. VALOVENРассматриваются образы зла в трилогии "Властелин колец" известного английского писателя, филолога, ученого-медиевиста, оксфордского профессора Джона ...
Валовень, О. Н.
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Digital Gaming and Tolkien, 1976-2015 [PDF]

open access: yes, 2016
‘Tolkien’ the cultural phenomenon is far bigger than J. R. R. Tolkien the author, or even J. R. R. Tolkien the author-and-oeuvre. When Christopher Tolkien asserted in 2012 that his father’s legacy has been rendered monstrous he blamed its fate on the ...
Young, Helen
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Building Imaginary Worlds (2012) by Mark J.P. Wolf and Revisiting Imaginary World (2016) edited by Mark J.P. Wolf [PDF]

open access: yes, 2017
Book review of Building Imaginary Worlds (2012) by Mark J.P. Wolf and Revisiting Imaginary Worlds (2016), edited by Mark J.P.
Higgins, Andrew
core   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Tolkien Among the Moderns (2015), ed. by Ralph C. Wood [PDF]

open access: yes, 2018
Book review by Robin Anne Reid of Tolkien Among the Moderns (2015) ed.
Reid, Robin A., Dr.
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Prominence of Pippin [PDF]

open access: yes, 2015
When building a fictional world as involved and vast as that of J.R.R. Tolkien’s multiple drafts are a must in order to work out the exact details and to make sure that all the possible loose ends are tied up and addressed.
Sunderlage, Jasmine
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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