Impact of Different Drying Processes on the Physico-Chemical Properties of Liquitablet Formulations Containing Lornoxicam [PDF]
PharmaceuticsBackground: Enhancing bioavailability is the target of most pharmaceutical research; this can be achieved by modifying the physico-chemical characteristics of poorly water-soluble drugs intended for oral administration using different techniques.
Csilla Balla-Bartos +3 more
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Comparison of tramadol and lornoxicam for the prevention of postoperative catheter-related bladder discomfort: a randomized controlled trial [PDF]
Perioperative Medicine, 2023 Background Catheter-related bladder discomfort (CRBD is a painful complication of intraoperative urinary catheterization after anaesthesia. We conducted this study to compare the effect of tramadol and lornoxicam for the prevention of postoperative CRBD.
Xin Liao +3 more
doaj +3 more sources
Iraqi Journal of Industrial Research, 2023 Lornoxicam was practically water insoluble and a nonsteroidal anti-inflammatory therapeutic agent thus associated with gastrointestinal tract (GIT) side effects.
Hayder Kadhim Drais
doaj +2 more sources
Kinetic Study of Lornoxicam Hydrolysis
Zanco Journal of Pure and Applied Sciences, 2020 Gastrointestinal tract (GIT) side effects due to the local action of lornoxicam considered the most common problem that associated with using of this analgesic drug.
sawsan hasan hammodi +1 more
doaj +5 more sources
Magnetic targeting of lornoxicam/SPION bilosomes loaded in a thermosensitive in situ hydrogel system for the management of osteoarthritis: Optimization, in vitro, ex vivo, and in vivo studies in rat model via modulation of RANKL/OPG. [PDF]
Drug Deliv Transl Res, 2023 Osteoarthritis is a bone and joint condition characterized pathologically by articular cartilage degenerative damage and can develop into a devastating and permanently disabling disorder.
Ibrahiem B, Shamma R, Salama A, Refai H.
europepmc +2 more sources
Efficacy of Lornoxicam as a Pre-emptive Analgesic in Mandibular Third Molar Surgery - A Comparative Study. [PDF]
Ann Maxillofac Surg, 2023 Introduction: The most common complication following third molar surgery is pain. The purpose of the study is to determine the efficacy of lornoxicam as a preventive analgesic in patients undergoing surgical removal of impacted mandibular third molars ...
Kaila V +5 more
europepmc +2 more sources
Optimizing lornoxicam-loaded poly(lactic-co-glycolic acid) and (polyethylene glycol) nanoparticles for transdermal delivery: <i>ex vivo</i>/<i>in vivo</i> inflammation evaluation. [PDF]
Nanomedicine (Lond)Aim: This study focused on developing a topical gel incorporating lornoxicam-loaded poly(lactic-co-glycolic acid) and polyethylene glycol (PLGA-PEG) blend nanoparticles to mitigate gastrointestinal (GIT) side effects and enhance therapeutic efficacy ...
Qaiser R +6 more
europepmc +2 more sources
Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach
Pharmaceuticals, 2022 The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD) approach. A randomized Box–Behnken experimental design was used to characterize the effect of the critical factors, such ...
Nawaf Almotairi +3 more
doaj +2 more sources
The Iraqi Journal of Veterinary MedicineLornoxicam (LOX) is a non-steroidal anti-inflammatory drug (NSAID) effective in managing ocular inflammation. Traditional delivery methods like liquid drops are cleared rapidly and may not provide sustained therapeutic levels, necessitating the ...
Riyam S Jafer, Hanan J Kassab
doaj +2 more sources
Saudi Pharmaceutical Journal, 2020 Rheumatoid arthritis (RA) is an autoimmune disease associated with severe joint pain. Herein, we report lornoxicam loaded cellulosic microsponge gel formulation with sustained anti-inflammatory effects that are required to manage arthritic pain.
Yeteng He +13 more
doaj +2 more sources