Results 131 to 140 of about 2,619 (179)
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Development and In Vitro Assessment of a Pluronic-coconut Oil-lecithin Organogel for Topical Delivery of Lornoxicam in Managing Cervical Spondylosis

Drug Delivery Letters
Topical delivery via organogels offers a promising method to deliver Lornoxicam directly to the target site with improved bioavailability, avoiding the issues associated with systemic administration.
Yeshna   +6 more
semanticscholar   +1 more source

Antithrombotic potential of lornoxicam and possible mechanistic pathways.

Journal of Pharmacology and Experimental Therapeutics
Lornoxicam is traditionally used as an anti-inflammatory and analgesic drug. Recent studies suggest that nonsteroidal anti-inflammatory drugs can influence platelet and coagulation pathways.
Waseem Khalid   +2 more
semanticscholar   +1 more source

Simultaneous Quantitation of Paracetamol and Lornoxicam in Presence of Five Related Substances and Toxic Impurities by a Selective HPLC-DAD Method.

Journal of AOAC International, 2022
OBJECTIVE This research describes the simultaneous quantitation of Paracetamol (PRM) and Lornoxicam (LRX) with five of their related substances and toxic impurities, including, 4-nitrophenol (NTP), 4-aminophenol (AMP), 4-chloroacetanilide (CAC), N ...
Amira F. El-Yazbi   +3 more
semanticscholar   +1 more source

Clinical Pharmacokinetics of Lornoxicam

Clinical Pharmacokinetics, 1998
Lornoxican (chlorotenoxicam) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class. Unlike other oxicams, lornoxicam has a relatively short plasma half-life (3 to 5 hours). Lornoxicam is eliminated following biotransformation to 5'-hydroxy-lornoxicam, which does not undergo enterohepatic recirculation.
N M, Skjodt, N M, Davies
openaire   +2 more sources

Physiologically based pharmacokinetic (PBPK) modeling of lornoxicam: Exploration of doses for CYP2C9 genotypes and patients with cirrhosis.

Journal of Pharmacy and Science, 2022
Lornoxicam physiologically based pharmacokinetic (PBPK) models were developed and validated on the basis of clinical pharmacokinetic results obtained by considering CYP2C9 genetic polymorphisms in healthy adult populations.
Seung-Hyun Jeong, J. Jang, Yong-Bok Lee
semanticscholar   +1 more source

Development of immediate release tablet formulations of lornoxicam with hot melt extrusion-based three-dimensional printing technology

Drug Development and Industrial Pharmacy
Introduction This study aims to develop immediate release tablet formulations of lornoxicam (LRX) using hot melt extrusion (HME)-based fused deposition modeling (FDM) focusing on the adjustment of drug release by arranging infill densities and evaluating
Aysel Yılmaz   +2 more
semanticscholar   +1 more source

Lornoxicam Solid Lipid Nanoparticle-Enriched Transdermal Gel: Development and Characterization

International Journal of Drug Delivery Technology
To develop antiinflammation and analgesic effects, scientists introduced lornoxicam (LRX) nanoemulsion, nanostructure lipid carriers, and solid lipid nanoparticles.
Vaibhav Dagaji Aher   +3 more
semanticscholar   +1 more source

Preoperative peritonsillar lornoxicam infiltration is not superior to intravenous lornoxicam for pain relief following tonsillectomy in adults

European Journal of Anaesthesiology, 2010
Nonsteroidal anti-inflammatory drugs have peripheral analgesic effects. We compared the efficacy of peritonsillar infiltration versus intravenous (i.v.) lornoxicam on pain relief after tonsillectomy in adults.Sixty adult patients scheduled for tonsillectomy were randomly assigned into three groups in a double-blind placebo-controlled study.
Salah A, Ismail, Hany A, Mowafi
openaire   +2 more sources

Fabrication and Characterization of Sustained-Release Eudragit RSPO Microsphere of Lornoxicam by Spray Drying Technique

Current Drug Therapy
Lornoxicam is a potent non-steroidal anti-inflammatory drug (NSAID) with strong analgesic properties; however, its short half-life necessitates frequent administration for sustained efficacy.
Hiren V. Patel   +3 more
semanticscholar   +1 more source

Formulation and Characterization of Emulgel Lornoxicam Containing Lemon Grass Oil as Penetration Enhancer.

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
INTRODUCTION Emulgel dosage form is an advanced form of transdermal drug de-livery. It is a combination of emulsion and gel in a definite ratio. Emulsions are incorporated into the gel with proper mixing. The emulsion present in emulgel can be either oil/
Vibha Kumari, Meenakshi Bajpai
semanticscholar   +1 more source

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