Results 171 to 180 of about 3,037 (201)
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Epidural lornoxicam administration – innocent
Journal of Clinical Neuroscience, 2007We aimed to determine the analgesic efficacy and clinical or histopathological neurotoxicity of epidural single-dose lornoxicam. Caudal epidural catheters were inserted into 28 rabbits, divided into four groups, on day 1. Pain latency and degree of motor and sensory loss for each animal for different concentrations of lornoxicam were determined on day ...
Canduz, Basak +7 more
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Clinical Pharmacokinetics of Lornoxicam
Clinical Pharmacokinetics, 1998Lornoxican (chlorotenoxicam) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class. Unlike other oxicams, lornoxicam has a relatively short plasma half-life (3 to 5 hours). Lornoxicam is eliminated following biotransformation to 5'-hydroxy-lornoxicam, which does not undergo enterohepatic recirculation.
N M, Skjodt, N M, Davies
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Formulation and evaluation of proniosomes containing lornoxicam
Drug Delivery and Translational Research, 2016Proniosomes are the new generation provesicular drug delivery system of non-ionic surfactant, lecithin and cholesterol which upon reconstitution get converted into niosomes. The objective of current study was to develop stable and sustain transdermal delivery system for lornoxicam.
Madan, Jyotsana R. +2 more
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European Journal of Anaesthesiology, 2010
Nonsteroidal anti-inflammatory drugs have peripheral analgesic effects. We compared the efficacy of peritonsillar infiltration versus intravenous (i.v.) lornoxicam on pain relief after tonsillectomy in adults.Sixty adult patients scheduled for tonsillectomy were randomly assigned into three groups in a double-blind placebo-controlled study.
Salah A, Ismail, Hany A, Mowafi
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Nonsteroidal anti-inflammatory drugs have peripheral analgesic effects. We compared the efficacy of peritonsillar infiltration versus intravenous (i.v.) lornoxicam on pain relief after tonsillectomy in adults.Sixty adult patients scheduled for tonsillectomy were randomly assigned into three groups in a double-blind placebo-controlled study.
Salah A, Ismail, Hany A, Mowafi
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Lornoxicam in clinical practice.
Postgraduate medical journal, 1991Three studies reported here have confirmed that lornoxicam is effective in osteoarthritis and the ideal dose appears to be 12 mg daily. Overall, lornoxicam appears to be a useful drug in the treatment of both osteo- and rheumatoid arthritis, from the data presently available.
H, Berry, S, Ollier
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Lornoxicam Salts: Crystal Structures, Conformations, and Solubility
Crystal Growth & Design, 2014Lornoxicam (LXM), a nonsteroidal anti-inflammatory drug (NSAID), is an amphiprotic molecule that exists as a zwitterion in the solid state. The formation of two strong intramolecular N+–H···O and N–H···O– hydrogen bonds in a stable six-member ring geometry, S(6), renders this otherwise flexible molecule in a rigid conformation (conformer A).
Kuthuru Suresh, Ashwini Nangia
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Pharmacokinetics of lornoxicam in man.
Postgraduate medical journal, 1991Clinical phase I pharmacokinetic studies with lornoxicam were performed with the 4 mg dose of lornoxicam. Lornoxicam was administered as an aqueous solution both orally and intravenously to young, healthy, male volunteers. The total excretion of lornoxicam via urine and faeces after oral administration was determined by administering 14C-labelled ...
G, Hitzenberger +3 more
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Clinical pharmacokinetic studies with lornoxicam.
Postgraduate medical journal, 1991Pharmacokinetic data from several studies in young and elderly human subjects are reviewed. Lornoxicam appears to be extensively metabolized and no unchanged drug has been found in the urine. It has a relatively short elimination half-life (about 4 hours), and no significant differences in pharmacokinetic data have been found between young and elderly ...
P, Turner, A, Johnston
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