Results 181 to 190 of about 4,656 (255)

Antithrombotic potential of lornoxicam and possible mechanistic pathways

The Journal of Pharmacology and Experimental Therapeutics
Lornoxicam is traditionally used as an anti-inflammatory and analgesic drug. Recent studies suggest that nonsteroidal anti-inflammatory drugs can influence platelet and coagulation pathways. However, the antithrombotic and cardiopulmonary protective potential of lornoxicam remains unexplored.
Waseem, Khalid, Arif-Ullah, Khan, Fawad, Ali   +2 more
openaire   +3 more sources

Presumptive Lornoxicam Intoxication in Four Dogs

Topics in Companion Animal Medicine, 2021
Lornoxicam is a nonsteroidal anti-inflammatory drug extensively used in human medicine, which is not approved for canine use. Lornoxicam intoxication has been rarely reported in dogs. Four dogs of various breeds, aged 7 months to 10 years, were admitted with a recent history of melena, anorexia and depression, occurring 1-4 days after the ingestion of ...
Vicky, Karakitsou, Katerina, Adamama-Moraitou, Lysimachos G, Papazoglou, George, Kazakos, Dimitrios, Timiou, Thomas, Polydoros, Anatoli, Tahmazidou, Mathios E, Mylonakis   +7 more
openaire   +2 more sources

Principles of White Analytical Chemistry and Design of Experiments to Stability-Indicating Chromatographic Method for Simultaneous Estimation of Thiocolchicoside and Lornoxicam.

Journal of AOAC International, 2023
BACKGROUND A variety of chromatographic methods have been published for the stability evaluation of thiocolchicoside and lornoxicam. Nevertheless, the development of chromatographic methods requires the use of neurotoxic and teratogenic organic solvents ...
P. Prajapati, V. Pulusu, Shailesh A Shah
semanticscholar   +1 more source

Lornoxicam bei gynäkologischen Eingriffen

Schmerz, 2003
R Likar
exaly   +2 more sources

Lornoxicam

2011
A comprehensive profile on lornoxicam, the oxicam nonsteroidal anti-inflammatory agent which is used in the muscular skeletal and joint disorders such as osteoarthritis and rheumatoid arthritis, is prepared. This profile contains the following sections: description, uses and applications, methods of preparation, physical characteristics, methods of ...
Mahrous O, Ahmed, Abdullah A, Al-Badr
openaire   +3 more sources

Design, Characterization and In Vivo Performance of Solid Lipid Nanoparticles (SLNs)-Loaded Mucoadhesive Buccal Tablets for Efficient Delivery of Lornoxicam in Experimental Inflammation.

International journal of pharmaceutics, 2022
Lornoxicam (LRX) is a potent nonsteroidal anti-inflammatory drug (NSAID) used extensively to manage pain and inflammatory conditions. However, the drug possesses poor aqueous solubility (i.e., BCS class II) and a short half-life (3-4h).
Moataz B. Zewail, Gihan F. Asaad, Salma M. Swellam, Sama M. Abd-allah, Sahar K Hosny, Salma K. Sallah, Jehan E Eissa, Salma S Mohamed, Walaa A. El-Dakroury   +8 more
semanticscholar   +1 more source

Formulation development of Lornoxicam loaded heat triggered ocular in-situ gel using factorial design

Drug Development and Industrial Pharmacy, 2023
Objective In the current research, lornoxicam-loaded in situ gels were developed, and their potential usage in ocular inflammation was evaluated. Significance Lornoxicam cyclodextrin complex prepared with hydroxypropyl methylcellulose and poloxamer P407 ...
H. Polat, Sedat Ünal, Eren Aytekin, N. F. Karakuyu, Esra Pezik, Muhammet Kerim Haydar, Nihat Kurt, Osman Doğan, Behzad Mokhtare   +8 more
semanticscholar   +1 more source

Epidural lornoxicam administration – innocent

Journal of Clinical Neuroscience, 2007
We aimed to determine the analgesic efficacy and clinical or histopathological neurotoxicity of epidural single-dose lornoxicam. Caudal epidural catheters were inserted into 28 rabbits, divided into four groups, on day 1. Pain latency and degree of motor and sensory loss for each animal for different concentrations of lornoxicam were determined on day ...
Canduz, Basak, Aktug, Huseyin, Mavioglu, Oemuer, Erkin, Yueksel, Yilmaz, Ozlem, Uyanikgil, Yigit, Korkmaz, Huelya, Baka, Meral   +7 more
openaire   +3 more sources

UV-Spectrophotometric Method Development and Determination of Suitable Medium for Lornoxicam by Comparing In-Between Three Body Fluids

Asian Journal of Pharmaceutical Analysis
The study was aimed to create and verify a new, straight-forward, accurate, and specific UV-Spectrophotometric analysis method of Lornoxicam, by comparing in-between three different types of body fluids, having three different pH, like a) gastric fluid ...
Sourav Duari, Ayan Das, R. Pal
semanticscholar   +1 more source

Formulation, Optimization, and Evaluation of Lornoxicam-Loaded Novasomes for Targeted Ulcerative Colitis Therapy: In Vitro and In Vivo Investigations.

Journal of drug targeting (Print)
The purpose of this work was to create and assess Lornoxicam (LOR) loaded Novasomes (Novas) for the efficient treatment of ulcerative colitis. The study was performed using a 23 factorial design to investigate the impact of several formulation variables.
Asmaa Badawy Darwish, Abeer Salama, Inas Essam Ibrahim Al-Samadi   +2 more
semanticscholar   +1 more source