Prevention of intimal thickening after endothelial removal by a nonpeptide angiotensin II receptor antagonist, losartan [PDF]
, 1992 Hiroshi Azuma +2 more
openalex +1 more source
The interplay between heart failure and chronic kidney disease
Diabetes, Obesity and Metabolism, Volume 27, Issue 7, Page 3568-3582, July 2025.Abstract Chronic kidney disease (CKD) and heart failure (HF) are two globally prevalent, independent, long‐term conditions, which often coexist in an individual and display a bidirectional yet interconnected relationship. The presence of CKD often leads to the development of HF and vice versa, which propagates the worsening of each disease, reflecting ...
Anuradha Lala +2 more
wiley +1 more source
OncoTarget, 2017 Drugs that target the Renin-Angiotensin System (RAS) have recently come into focus for their potential utility as cancer treatments. The use of Angiotensin Receptor Blockers (ARBs) and Angiotensin-Converting Enzyme (ACE) Inhibitors (ACEIs) to manage ...
Rhiannon Coulson +22 more
semanticscholar +1 more source
Internal Medicine Journal, Volume 55, Issue 7, Page 1169-1173, July 2025.Abstract Background Serum uric acid (SUA) has been associated with an increased risk of cardiovascular disease (CVD) in both the general population and individuals with type 2 diabetes (T2DM). Identification of high‐risk individuals is crucial for the primary prevention of CVD.
Funda Yildirim Borazan +3 more
wiley +1 more source
Losartan reduces ensuing chronic kidney disease and mortality after acute kidney injury
Scientific Reports, 2016 Acute kidney injury (AKI) is an important risk factor for incident chronic kidney disease (CKD). Clinical studies disclose that ensuing CKD progresses after functional recovery from AKI, but the underlying mechanisms remain illusive. Using a murine model
Shun-Yang Cheng +12 more
semanticscholar +1 more source
Angiotensin II receptor blockade attenuates the deleterious effects of exercise training on post-MI ventricular remodelling in rats [PDF]
, 2017 Objectives: The effects of exercise training on LV remodelling following large anterior myocardial infarction (MI) remains controversial. Blockade of the renin-angiotensin system has been shown to prevent ventricular dilation and deleterious remodeling ...
Apstein, Carl S. +5 more
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Comparison of the regional haemodynamic effects of the AT1‐receptor antagonists, losartan and EXP 3174, in water‐deprived Brattleboro rats [PDF]
, 1993 Robert E. Widdop +3 more
openalex +1 more source
Pigment Cell &Melanoma Research, Volume 38, Issue 4, July 2025.ABSTRACT The unique pharmacokinetics of BRAF and MEK inhibitors make patients vulnerable to drug–drug interactions (DDIs), which may compromise treatment efficacy in metastatic melanoma. This study evaluates the impact of DDIs on clinical outcomes in patients with metastatic melanoma treated with BRAF/MEK inhibitors.
Silvia Mezi +14 more
wiley +1 more source
Losartan-sensitive AII Receptors Linked to Depolarization- dependent Cortisol Secretion through a Novel Signaling Pathway [PDF]
, 1995 Boris Mlinar +2 more
openalex +1 more source
Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren‐2 transgenic rats [PDF]
, 1997 Concepción Peiró +6 more
openalex +1 more source