Results 41 to 50 of about 27,143 (245)

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

open access: yesAdvanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang   +17 more
wiley   +1 more source

Risk preferences and the low-carbon agricultural technology adoption: Evidence from rice production in China

open access: yesJournal of Integrative Agriculture, 2023
Climate change which is mainly caused by carbon emissions is a global problem affecting the economic development and well-being of human society. Low-carbon agriculture is of particular significance in slowing down global warming and reaching the goal of
Hui MAO, Yu-rong QUAN, Yong FU
doaj   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong   +20 more
wiley   +1 more source

The Loss-Averse Retailer’s Order Decisions Under Risk Management

open access: yesMathematics, 2019
This paper characterizes the retailer’s loss aversion by introducing a loss aversion coefficient and proposes a new loss aversion utility function for the retailer.
Felix T. S. Chan, Xinsheng Xu
doaj   +1 more source

Loss-Aversively Fair Classification [PDF]

open access: yesProceedings of the 2019 AAAI/ACM Conference on AI, Ethics, and Society, 2019
8 pages, Accepted at AIES ...
Junaid Ali 0001   +3 more
openaire   +3 more sources

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

Loss Aversion in Financial Markets

open access: yesJournal of Mechanism and Institution Design, 2019
Experimental evidence suggests that people are more sensitive to losses than gains by a factor of about two. Researchers have drawn implications from loss aversion to understand various aspects of individual decisions and asset prices in financial ...
Liyan Yang
doaj   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

open access: yesAdvanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong   +6 more
wiley   +1 more source

From Devices to Systems: Integration Strategies for Micro‐Supercapacitors in Microsystems

open access: yesAdvanced Science, EarlyView.
Micro‐supercapacitors are evolving from device‐level energy storage toward system‐level functional units in integrated microsystems. This Review presents a system‐oriented design framework in which integration serves as the key link between application requirements, system constraints, device architectures, and material selection. Monolithic and hybrid
Zhuohao Liu, Gang Li, Kaiying Wang
wiley   +1 more source

Is loss-aversion magnitude-dependent? Measuring prospective affective judgments regarding gains and losses [PDF]

open access: yesJudgment and Decision Making, 2017
Prospect Theory proposed that the (dis)utility of losses is always more than gains due to a phenomena called ‘loss-aversion’, a result obtained in multiple later studies over the years.
Sumitava Mukherjee   +3 more
doaj  

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