Results 101 to 110 of about 389,923 (287)

Effective Loss Minimization and Allocation of Unbalanced Distribution Network

open access: yesEnergies, 2017
An efficient distribution network must be able to supply power with good voltage profile. The main objective of the proposed work is to allocate losses of the unbalanced distribution network by the firefly algorithm in regulated and deregulated ...
Manvir Kaur, Smarajit Ghosh
doaj   +1 more source

Sign-Constrained Regularized Loss Minimization

open access: yes, 2017
In practical analysis, domain knowledge about analysis target has often been accumulated, although, typically, such knowledge has been discarded in the statistical analysis stage, and the statistical tool has been applied as a black box. In this paper, we introduce sign constraints that are a handy and simple representation for non-experts in generic ...
Kato, Tsuyoshi   +2 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Minimization of transmission loss using distributed generation approach

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization, 2018
The goal of this work is to calculate the total loss in the system and minimize this loss by implementation of distributed generation (DG) technology. In this paper, load flow analysis method is followed to calculate the loss in the system in conjunction
Lamin Chaantrea Miky, Singh Arvind Kumar
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

MINIMAL LOSS RECONFIGURATION CONSIDERING RANDOM LOAD: APPLICATIONS TO REAL NETWORKS RECONFIGURACIÓN A MÍNIMAS PÉRDIDAS, CONSIDERANDO LA ALEATORIEDAD DE LA CARGA: APLICACIÓN A SISTEMAS

open access: yesIngeniare: Revista Chilena de Ingeniería, 2008
This paper approaches the minimal loss reconfiguration problem, taking into account the load variations of the systems, through a stochastic reconfiguration process. The Monte Carlo method is used to consider the natural load variation.
Hugo Opazo Mora   +4 more
doaj  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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