Results 201 to 210 of about 91,338 (344)

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Genomic Insights Into Red Squirrels in Scotland Reveal Loss of Heterozygosity Associated With Extreme Founder Effects. [PDF]

Evol Appl
Marr MM, Humble E, Lurz PWW, Wilson LA, Milne E, Beckmann KM, Schoenebeck J, Fung UY, Kitchener AC, Kortland K, Edwards C, Ogden R.   +11 more
europepmc   +1 more source

Analysis of loss of heterozygosity in neoplastic nodules induced by diethylnitrosamine in the resistant BFF1 rat strain [PDF]

, 1999
Manuela Gariboldi
openalex   +1 more source

Genome sequencing and mapping reveal loss of heterozygosity as a mechanism for rapid adaptation in the vegetable pathogen Phytophthora capsici.

Molecular Plant-Microbe Interactions, 2012
K. Lamour, J. Mudge, D. Gobena, O. Hurtado-Gonzales, J. Schmutz, A. Kuo, Neil A. Miller, B. J. Rice, S. Raffaele, L. Cano, A. Bharti, R. Donahoo, S. Finley, E. Huitema, Jonathan P. Hulvey, D. Platt, A. Salamov, A. Savidor, Rahul Sharma, R. Stam, D. Storey, M. Thines, J. Win, B. Haas, D. Dinwiddie, J. Jenkins, James R. Knight, J. Affourtit, Cliff Han, O. Chertkov, E. Lindquist, C. Detter, I. Grigoriev, S. Kamoun, S. Kingsmore   +34 more
semanticscholar   +1 more source

Altered Primary Somatosensory Neuron Development in a Pten Heterozygous Model for Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social interactions, repetitive behaviors, and hyper‐ or hyposensitivity to sensory stimuli. The cellular mechanisms underlying the emergence of abnormal sensory sensitivity in ASD are not fully understood.
Alejandra Fernandez, Nick Sarn, Charis Eng, Kevin M. Wright   +3 more
wiley   +1 more source

Analysis of biopsies of gastric cancer, intestinal and diffuse, and non-atrophic gastritis: an overview of loss of heterozygosity in Mexican patients. [PDF]

PeerJ
Larios-Serrato V, Valdez-Salazar HA, Torres J, Camorlinga M, Piña-Sánchez P, Minauro F, Ruiz-Tachiquín ME.   +6 more
europepmc   +1 more source

Loss of Heterozygosity in the Circulating Tumor DNA and CD138+ Bone Marrow Cells in Multiple Myeloma. [PDF]

Genes (Basel), 2023
Soloveva M, Solovev M, Nikulina E, Risinskaya N, Biderman B, Yakutik I, Obukhova T, Mendeleeva L.   +7 more
europepmc   +1 more source

Loss of Heterozygosity (LOH) Profiles—Validated Risk Predictors for Progression to Oral Cancer

Cancer Prevention Research, 2012
Lewei Zhang, C. Poh, Michele A. Williams, D. Laronde, K. Berean, Pamela J. Gardner, Huijun Jiang, Lang Wu, J. J. Lee, M. Rosin   +9 more
semanticscholar   +1 more source

Recurrent fexuprazan‐induced liver injury following unintentional re‐exposure

British Journal of Clinical Pharmacology, EarlyView.
Fexuprazan, a potassium‐competitive acid blocker, is increasingly used for the treatment of gastroesophageal reflux disease in South Korea. While generally well tolerated, data regarding its hepatotoxic potential are scarce. We report a case of idiosyncratic drug‐induced liver injury in a 61‐year‐old woman following 2 months of fexuprazan therapy.
Sook Jin Seong, O Seong Kweon, Young‐Ran Yoon, Yu Kyung Kim, Yoo Na Kang, Se Young Jang   +5 more
wiley   +1 more source

Loss of Heterozygosity (LOH) Affecting HLA Genes in Breast Cancer: Clinical Relevance and Therapeutic Opportunities. [PDF]

Genes (Basel)
Garrido MA, Navarro-Ocón A, Ronco-Díaz V, Olea N, Aptsiauri N.   +4 more
europepmc   +1 more source