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Loss of Heterozygosity

, 2016
Loss of heterozygosity (LOH) is a genetic event frequently observed in many cancer types. The loss of one allele of a genetic locus can have multiple possible functional effects including haploinsufficiency, loss of gene expression and being the second ...
Kylie L. Gorringe
semanticscholar   +1 more source

Evidence of loss of heterozygosity of the PTCH gene in orthokeratinized odontogenic cyst.

Journal of Oral Pathology & Medicine, 2011
The orthokeratinized odontogenic cyst (OOC) is an odontogenic cyst of unknown etiology. Clinical, histological, and biological differences are reported between keratocystic odontogenic tumor (KOT) and OOC. PTCH is a tumor suppressor gene related to sonic
M. G. Diniz   +4 more
semanticscholar   +1 more source

Loss of heterozygosity by SCRaMbLEing

Science China Life Sciences, 2019
Yunxiang Li   +5 more
semanticscholar   +1 more source

Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair-deficient Prostate Cancer.

European Urology, 2017
M. Annala   +15 more
semanticscholar   +1 more source

Loss of heterozygosity analysis in malignant gliomas

Brain Tumor Pathology, 2011
M. Mizoguchi   +6 more
semanticscholar   +1 more source

Loss of p53 in esophageal squamous cell carcinoma and the correlation with survival: Analyses of gene mutations, protein expression, and loss of heterozygosity in Japanese patients

Journal of Surgical Oncology, 2011
A. Egashira   +8 more
semanticscholar   +1 more source

High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

Nature Biotechnology, 2010
Elisa Närvä   +21 more
semanticscholar   +1 more source

Loss of Heterozygosity

, 2013
H. Schwarzenbach
semanticscholar   +1 more source

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