Results 151 to 160 of about 1,405,729 (293)

Analysis of the Lost Circulation Problem

Fluid Dynamics & Materials Processing, 2023
Xingquan Zhang, Renjun Xie, Kuan Liu, Yating Li, Yuqiang Xu   +4 more
openaire   +1 more source

Feature enhancement-based intelligent monitoring of lost circulation risk

To address the challenge of limited effective data samples in lost circulation, a common yet complex risk in oil and gas drilling, this study proposes an intelligent diagnosis model for lost circulation risk based on a 1D-CNN and LSTM hybrid network.
Zhao-Peng Zhu, Shi-Jie Xiao, Yuan-Sen Wei, Long Chena, Ning Li, De-Tao Zhou, Chong-Yuan Zhang, Cheng-Kai Zhang, Xiao-Guang Wu   +8 more
core   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Development and Application of Oil-Based Thermo-Responsive Gel Lost Circulation Material SBR-g-PSA. [PDF]

Gels
Liu Z, Nie C, Xiao F, Chen M, Liu M, Feng Q, Yue C.   +6 more
europepmc   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Preparation and High-Temperature Fracture-Sealing Performance of an Oil-Absorbing Swelling Gel for Lost-Circulation Control in Oil-Based Drilling Fluids. [PDF]

Gels
Zhang K, Liang Q, Chen X, Yan J, Guo D, Pan Y, Zhu X, Jiang X, Yang J.   +8 more
europepmc   +1 more source

Engineering an Artificial Metalloenzyme for Efficient Photo‐Enzymatic CO2 Conversion

Advanced Science, EarlyView.
We built a light‐driven artificial metalloenzyme by covalently conjugating formate dehydrogenase (FDH) with a tailored rhodium complex (Rh‐L6) to overcome spatial‐separation‐limited electron transfer. This integration boosts NADH regeneration and CO2 conversion, giving 2.31‐fold higher formate yield than physical mixtures, due to a narrowed bandgap and
Mengxue Kang, Yan Chu, Zhichun Xu, Jiao Feng, Ganlu Li, Kequan Chen, Hui Li   +6 more
wiley   +1 more source