Results 91 to 100 of about 6,468,446 (336)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
, 2017 In this paper, we study various parallelization schemes for the Variable Neighborhood Search (VNS) metaheuristic on a CPU-GPU system via OpenMP and OpenACC.
Antoniadis, Nikolaos, Sifaleras, Angelo
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
A Polynomial Time Algorithm for a Deterministic Joint Pricing and Inventory Model [PDF]
In this paper we consider the uncapacitated economic lot-size model, where demand is adeterministic function of price. In the model a single price need to be set for all periods.
Heuvel, W. van den, Wagelmans, A.P.M.
core +1 more source
A relax-and-fix with fix-and-optimize heuristic applied to multi-level lot-sizing problems [PDF]
, 2015 In this paper, we propose a simple but efficient heuristic that combines construction and improvement heuristic ideas to solve multi-level lot-sizing problems.
Akartunali, Kerem +4 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Mathematical Programming for Lot Sizing and Production Scheduling in Foundries
Archives of Foundry Engineering, 2014 The problem considered in the paper is motivated by production planning in a foundry equipped with the furnace and casting line, which provides a variety of castings in various grades of cast iron/steel for a large number of customers.
Duda J., Stawowy A., Basiura R.
doaj +1 more source
Forecast accuracy, information technologies and the performance of inventory policies under multi-level rolling schedule environments [PDF]
Our incentive is to study the behaviour of lot-sizing rules in a multi-level context when forecast demand is subject to changes within the forecast window.
Dellaert,Nico, Jeunet,Jully
core +1 more source
A heuristic approach for big bucket multi-level production planning problems [PDF]
, 2009 Multi-level production planning problems in which multiple items compete for the same resources frequently occur in practice, yet remain daunting in their difficulty to solve. In this paper, we propose a heuristic framework that can generate high quality
Akartunali, Kerem, Miller, Andrew
core +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source