Results 151 to 160 of about 493,362 (305)

A Polynomial Time Algorithm for a Deterministic Joint Pricing and Inventory Model

open access: yes
In this paper we consider the uncapacitated economic lot-size model, where demand is adeterministic function of price. In the model a single price need to be set for all periods.
Wagelmans, A.P.M., Heuvel, W. van den
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A forward algorithm for capacitated lot sizing problem with lost sales

open access: yes, 2004
This paper addresses a single item dynamic lot sizing problem where the inventory capacity is limited and shortages are allowed. Unsatisfied demand cannot be backlogged, which means lost sales. Costs are assumed to be time-varying.
Chu F(储峰)   +3 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A comparison of two lot sizing-sequencing heuristics for the process industry

open access: yes
Production Models ...
Selen, W.J., Heuts, R.M.J., Seidel, H.P.
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Lot sizing models with backlog or out-sourcing

open access: yes, 2004
This paper addresses a single item capacitated dynamic lot sizing problem. We consider backlogging models as well as out-sourcing models to minimize the total cost. The production, holding and backlogging or out-sourcing cost functions considered in this
Chu F(储峰)   +2 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Time bucket size and lot-splitting approach

open access: yes
We address the problem of lot splitting for various time bucket lengths in MRP systems. Two approaches for lot splitting can be applied: either use the same (equal) or a variable number of subbatches.
Riezebos, Jan
core  

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