Results 141 to 150 of about 493,362 (305)
Dynamic Programming Algorithms for Lot-Sizing Problems
Lot-sizing problem has been extensively researched in many aspects. In this review, we summarize key points of dynamic programming algorithms in lot-sizing problems and give some hints helping further designing algorithms for more variations of lot ...
ザン, ピン, Zhan, Ping
core
Optimizing campaign sizing policies: an application to a real-life setting. [PDF]
This paper presents an integrated production inventory model that enables to capture the tradeoffs between average inventory, production capacity and customer service level in a semiprocess industry setting. The model includes different features that are
Van Nieuwenhuyse, Inneke +2 more
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Lot-sizing: production planning methods and models
openProgrammazione lineare intera mista, programmazione dinamica, modelli di pianificazione della produzione, The Uncapacitated Lot-sizing problem (LS-U), variante di LS-U con vendite e scorte di sicurezza, variante di LS-U con costi fissi di stoccaggio ...
CIUFFREDA, SARA
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Some new properties for capacitated lot-sizing problem with bounded inventory and stockouts
Some new properties for capacitated lot-sizing problem with bounded inventory and ...
Chu F(储峰) +3 more
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source

