Results 91 to 100 of about 86,998 (307)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Lot Sizing Based on Stochastic Demand and Service Level Constraint

open access: yesمدیریت تولید و عملیات, 2012
Considering its application, stochastic lot sizing is a significant subject in production planning. Also the concept of service level is more applicable than shortage cost from managers' viewpoint.
hajar shirneshan   +2 more
doaj  

Forecast accuracy, information technologies and the performance of inventory policies under multi-level rolling schedule environments [PDF]

open access: yes
Our incentive is to study the behaviour of lot-sizing rules in a multi-level context when forecast demand is subject to changes within the forecast window.
Dellaert,Nico, Jeunet,Jully
core   +1 more source

On alternative mixed integer programming formulations and LP-based heuristics for lot-sizing with setup times [PDF]

open access: yes, 2006
We address the multi-item, capacitated lot-sizing problem (CLSP) encountered in environments where demand is dynamic and to be met on time. Items compete for a limited capacity resource, which requires a setup for each lot of items to be produced causing
Denizel, Meltem   +2 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A relax-and-fix with fix-and-optimize heuristic applied to multi-level lot-sizing problems [PDF]

open access: yes, 2015
In this paper, we propose a simple but efficient heuristic that combines construction and improvement heuristic ideas to solve multi-level lot-sizing problems.
Akartunali, Kerem   +4 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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