Results 41 to 50 of about 10,014,931 (288)

Very Strong Hydrogen Bond in Nitrophthalic Cocrystals

Molecules
This work presents the studies of a very strong hydrogen bond (VSHB) in biologically active phthalic acids. Research on VSHB comes topical due to its participation in many biological processes.
Kinga Jóźwiak, Aneta Jezierska, Jarosław J. Panek, Andrzej Kochel, Barbara Łydżba-Kopczyńska, Aleksander Filarowski   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Shortest Symmetrical O−H···O Hydrogen Bond Has a Low-Barrier Double-Well Potential

, 2016
The strong hydrogen bond, in which a hydrogen atom is centered between two electronegative atoms in a single minimum potential has been widely discussed but rarely definitively observed.
John A. Cowan (2700151), Gerard S. Harbison (146021), Alexander I. Kolesnikov (1609597), John A. Belot (2706457), Young-Sik Kye (2716054), Xingang Zhao (1862920), Joanna Clark (2716051), Arthur J. Schultz (1605997), Carter Silvernail (2716057)   +8 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Power-to-Hydrogen and Hydrogen-to-X : system Analysis of the techno-economic, legal, and regulatory conditions

, 2021
P2X pathway definitions has the aim to clarify terminologies that are often used but with different meanings or intentions which leads to misunderstanding and ambiguity.
Funez, C., Mansilla, C., Prost, J., Dickinson, R., Lucchese, P., Samsatli, S., Leaver, Jonathan, Grand-Clement, L., Tilli, O.   +8 more
core  

Hydrogen-Bond-Assisted Symmetry Breaking in a Network of Chiral Metal-Organic Assemblies. [PDF]

, 2019
Herein we elucidate the interplay of chiral, chelate, solvent, and hydrogen-bonding information in the self-assembly of a series of new three-dimensional metal-organic architectures.
Patrick Pröhm (6239552), Felix J. Rizzuto (4325368), Alex J. Plajer (6239555), Jake L. Greenfield (1650277), Jonathan R. Nitschke (1261920)   +4 more
core   +2 more sources

Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond

, 2022
Here, we report a novel mechanism to selectively degrade target proteins. 3-(3-Phenoxybenzyl)­amino-β-carboline (PAC), a tubulin inhibitor, promotes selective degradation of αβ-tubulin heterodimers.
Haoyu Ye (6588242), Lijuan Chen (150349), Wei Yan (4327), Dingguo Xu (1856620), Yong Li (15029), Heying Pei (336996), Qiang Qiu (412276), Yamei Yu (3687013), Yuquan Wei (267570), Lu Niu (2589736), Jianhong Yang (3007035), Liang Ouyang (4669825), Ruihan Wang (234022), Haoche Wei (4780050), Qiang Chen (114038)   +14 more
core   +1 more source

H2BASQUE - TECHNOLOGIES FOR BOOSTING THE HYDROGEN ECONOMY IN THE BASQUE COUNTRY: GREEN HYDROGEN PRODUCTION

, 2022
Publisher Copyright: © 2022 Proceedings of WHEC 2022 - 23rd World Hydrogen Energy Conference: Bridging Continents by H2. All rights reserved.H2BASQUE is a strategic project funded by the Basque Government for developing innovative technologies (and their
Alcaide, Francisco, Irigoyen, Jone, Doppiu, Stefania, Fernandez, Ekain, Oregui-Bengoechea, Mikel, Berasategui, Eva G., Unzueta, Elias, Sanchez, Beatriz Calleja   +7 more
core   +1 more source

An Ab Initio RRKM-Based Master Equation Study for Kinetics of OH-Initiated Oxidation of 2-Methyltetrahydrofuran and Its Implications in Kinetic Modeling

Energies, 2023
Cyclic ethers (CEs) can be promising future biofuel candidates. Most CEs possess physico-chemical and combustion indicators comparable to conventional fuels, making them suitable for internal combustion engines. This work computationally investigates the
Tam V.-T. Mai, Thanh Q. Bui, Nguyen Thi Ai Nhung, Phan Tu Quy, Krishna Prasad Shrestha, Fabian Mauss, Binod Raj Giri, Lam K. Huynh   +7 more
doaj   +1 more source

Pseudo-Jahn-Teller origin of the low barrier hydrogen bond in N2H7+ [PDF]

The Journal of Chemical Physics, 2008
The microscopic origin and quantum effects of the low barrier hydrogen bond (LBHB) in the proton-bound ammonia dimer cation N2H7+ were studied by means of ab initio and density-functional theory (DFT) methods. These results were analyzed in the framework of vibronic theory and compared to those obtained for the Zundel cation H5O2+.
García Fernández, Pablo (físico), García Canales, L., García Lastra, J.M., Junquera Quintana, Francisco Javier, Moreno Mas, Miguel, Aramburu-Zabala Higuera, José Antonio   +5 more
openaire   +4 more sources