Results 61 to 70 of about 796,368 (357)
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Fatigue-creep behaviors of Ni–Fe based superalloy under various testing conditions
Journal of Materials Research and Technology, 2021 The fatigue-creep properties of Ni–Fe based superalloy with varying strain amplitude, temperature and holding duration are studied in ambient air. The results demonstrated that the number of cycles decreases greatly with increasing strain amplitude from ...
Zilong Zhao +9 more
doaj +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Science and Technology of Advanced Materials: Methods, 2023 The new fatigue data sheet, No. 133, discloses low- and high-cycle fatigue properties of A2017-T4 aluminium alloys. Two types of low-cycle fatigue tests were conducted under strain-controlled conditions.
Yoshiyuki Furuya +4 more
doaj +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Identification of low cycle fatigue parameters
Applied and Computational Mechanics, 2009 The article describes a new approach to the processing of experimental data coming from low-cycle fatigue (LCF) tests. The data may be either tables from the standard tests, or a time series of loading processes and corresponding numbers of cycles to ...
Balda M.
doaj
MATEC Web of Conferences, 2018 In the present article, the low-cycle fatigue lifetime of carbon/epoxy laminated composites has been investigated. The sensitivity analysis has been also performed to study effects of the displacement amplitude and the loading frequency on the low-cycle ...
Azadi Mohammad +2 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Assessment of Durability of the Toothed Segment Based on FEM Analysis and Low Fatigue Cycle Test
Archives of Foundry Engineering, 2016 The development of a novel design for the toothed segment of drive transmission in longwall shearer is expected to significantly reduce the cost of individual components of the feed system and the related work of repair and renovations, increasing at the
Piekło J., Maj M., Żuczek R., Pysz S.
doaj +1 more source