Results 41 to 50 of about 403,471 (309)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
MATEC Web of Conferences, 2018 In the present article, the low-cycle fatigue lifetime of carbon/epoxy laminated composites has been investigated. The sensitivity analysis has been also performed to study effects of the displacement amplitude and the loading frequency on the low-cycle ...
Azadi Mohammad +2 more
doaj +1 more source
Assessment of Durability of the Toothed Segment Based on FEM Analysis and Low Fatigue Cycle Test
Archives of Foundry Engineering, 2016 The development of a novel design for the toothed segment of drive transmission in longwall shearer is expected to significantly reduce the cost of individual components of the feed system and the related work of repair and renovations, increasing at the
Piekło J., Maj M., Żuczek R., Pysz S.
doaj +1 more source
Cumulative Damage in Very High/Low Cycle Combined Fatigue for TC21 Titanium Alloy
Crystals, 2022 The effect of low cycle fatigue (LCF) predamage with no precracks on very high cycle fatigue (VHCF) properties, and crack initiation characteristics for TC21 titanium alloy, was investigated.
Baohua Nie +7 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Study on high-low cycle fretting fatigue life of Inconel718 tenon structure
Hangkong gongcheng jinzhanThe turbine blades of aero-engines are subjected to cyclic high-low cycle loads in actual service environments，which is a typical high-low cycle micro motion fatigue condition. The frequent occurrence of fatigue fracture in turbine blades due to fretting
YANG Xiaolin +3 more
doaj +1 more source
Micro-Deformation and Fracture Features of Ti834 Titanium Alloy under Fatigue Loading
Metals, 2023 A sustained load holding period imposed during fatigue loading is detrimental to material performances, causing a sharp decline in the fatigue life of near-α titanium alloys.
Ning Wang +4 more
doaj +1 more source
New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Arthritis Care &Research, EarlyView.Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs +15 more
wiley +1 more source
Effect of Prolonged Thermal Exposure on Low-Cycle Bending Fatigue Resistance of Low-Carbon Steel
Metals, 2022 Using a dynamic mechanical analyzer, the comparative studies of a low-cycle bending fatigue were carried out for AISI 1022 low-carbon steel after extreme thermal exposure, simulating the severe beyond-design-basis accident at nuclear power plants. In the
Sergey A. Nikulin +5 more
doaj +1 more source
Notch Effect on Torsional Low-Cycle Fatigue
International Journal of Materials Research, 1983 Öz bulunamadı.
GEVREK, M, GULEC, S
openaire +2 more sources