Results 261 to 270 of about 585,431 (288)
Some of the next articles are maybe not open access.
Clinical Laboratory, 2017
Malondialdehyde low-density lipoprotein (MDA-LDL) is a major form of oxidized LDL and considered to be more atherogenic than LDL. Information on major determinants of MDA-LDL and their association in subjects who are not under treatment for diabetes mellitus and dyslipidemia is limited.This study included 778 Japanese subjects who were not taking ...
Kengo, Moriyama, Eiko, Takahashi
openaire +2 more sources
Malondialdehyde low-density lipoprotein (MDA-LDL) is a major form of oxidized LDL and considered to be more atherogenic than LDL. Information on major determinants of MDA-LDL and their association in subjects who are not under treatment for diabetes mellitus and dyslipidemia is limited.This study included 778 Japanese subjects who were not taking ...
Kengo, Moriyama, Eiko, Takahashi
openaire +2 more sources
Low-density lipoprotein oxidation.
Italian heart journal : official journal of the Italian Federation of Cardiology, 2001Free radical mediated oxidation of low-density lipoproteins (LDL), which has been extensively studied in the last two decades, plays a central role in the development of the atherosclerotic plaque. Oxidation involves the lipid moiety of LDL in a chain reaction mechanism.
IULIANO, Luigi +2 more
openaire +2 more sources
Low-density lipoprotein binding assay using the calf adrenocortical low-density lipoprotein receptor
Clinical Biochemistry, 1994The low-density lipoprotein (LDL) receptor was purified to a semipure solubilized form from calf adrenocortical tissue. This receptor was found to be a suitable substitute for the human LDL receptor for studying human LDL binding. The apparent dissociation constant of the receptor from calf adrenocortical cells, using human LDL as the ligand, was found
P, Catomeris, R J, Thibert, T F, Draisey
openaire +2 more sources
Low Density Lipoproteins and Hypercholesterolemia
1989Coronary and vascular disease of atherosclerotic origin are the main causes of death and at the same time the most frequent reasons for early invalidity in the Federal Republic of Germany and other industrialized nations. In particular, coronary heart disease (CHD) is the major cause of death in middle-aged men.
G, Assmann, H, Funke, G, Schmitz
openaire +2 more sources
The low density lipoprotein receptor
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989The study of familial hypercholesterolemia at the molecular level has led to its advancement from a clinical syndrome to a fascinating experimental system. FH was first described 50 years ago by Carl Müller who concluded that the disease produces high plasma cholesterol levels and myocardial infarctions in young people, and is transmitted as an ...
openaire +2 more sources
Low-density Lipoproteins in Atherogenesis
2000It is well established that high levels of plasma cholesterol, particularly those associated with low-density lipoprotein (LDL), increase the risk of developing atherosclerosis. It is also clear that lowering plasma cholesterol levels can arrest or even reverse the progression of the disease [1,2].
openaire +1 more source
Low Density Lipoprotein Apheresis
2013Therapeutic plasma exchange volume is usually 3–5 L/session. Removal of positively charged particles as well as low density lipoprotein cholesterol improves focal segmental glomerulosclerosis and peripheral arterial disease. Angiotensin converting enzyme (ACE) inhibitors should be discontinued at least 2–3 days prior to low density ...
Kenjiro Honda, Kent Doi
openaire +1 more source
[Modified low-density lipoprotein].
Nihon rinsho. Japanese journal of clinical medicine, 1995Oxidative modification of low-density lipoprotein (LDL) has been implicated in the pathogenesis of coronary artery disease (CAD). Macrophages take up oxidized LDL via scavenger receptors, which is not regulated by cellular cholesterol contents, and oxidized LDL stimulates cholesterol esterification and this results in cellular cholesterol accumulation ...
H, Yoshida, H, Nakamura
openaire +1 more source
Mammalian Low Density Lipoproteins
1976During the past few years considerable advances have been made in the study of mammalian plasma low density lipoproteins. Although human LDL is of prime interest, mainly because of its association with atherosclerosis, many studies can most satisfactorily be carried out on animals, including work on the mechanisms of LDL production and metabolism, the ...
openaire +1 more source
Oxidised Low Density Lipoproteins
1993The evidence for the oxidative modification of low density lipoprotein (LDL) and its subsequent recognition by the scavenger receptors on macrophages in vitro is clear. The presence of oxidatively modified LDL in atherosclerotic lesions is well-recognised. However, the mechanism whereby LDL becomes oxidised in vivo is yet to be clarified.
openaire +1 more source