Results 121 to 130 of about 2,386 (174)

Effects of Losartan on Low‐Density Lipoprotein Apheresis

Therapeutic Apheresis, 1999
Abstract:The negative charges of dextran sulfate cellulose (DSC) used for low‐density lipoprotein (LDL) apheresis activate the intrinsic coagulation pathway, accompanied by bradykinin production. This study was undertaken to see whether an antagonist of angiotensin receptor (AT1), losartan, could be safely used in a patient treated by DSC‐LDL apheresis.
S, Kojima, Y, Yoshitomi, M, Saotome, K, Tanaka, M, Shida, M, Kuramochi   +5 more
openaire   +2 more sources

Role of Low-Density Lipoprotein Apheresis

The American Journal of Cardiology, 2005
Low-density lipoprotein (LDL) apheresis has been shown to reduce plasma levels of total cholesterol, LDL cholesterol, and lipoprotein(a). In addition to these lipoprotein changes, LDL apheresis induces atherosclerosis regression, improves myocardial perfusion and endothelial function, and may reduce cardiovascular event rates.
openaire   +2 more sources

Low Density Lipoprotein Apheresis

2013
Therapeutic plasma exchange volume is usually 3–5 L/session. Removal of positively charged particles as well as low density lipoprotein cholesterol improves focal segmental glomerulosclerosis and peripheral arterial disease. Angiotensin converting enzyme (ACE) inhibitors should be discontinued at least 2–3 days prior to low density ...
Kenjiro Honda, Kent Doi
openaire   +1 more source

Low-density lipoprotein apheresis therapy during pregnancy

The American Journal of Cardiology, 2000
Pregnancy in patients with severe hypercholesterolemia and coronary artery disease results in multiple problems both for mother and fetus; the most potent agents for low-density lipoprotein (LDL) cholesterol reduction, the HMG-CoA reductase inhibitors (statins) cannot be used during pregnancy.
L, Cashin-Hemphill, M, Noone, J F, Abbott, C A, Waksmonski, R S, Lees   +4 more
openaire   +2 more sources

Efficacy of Different Low‐Density Lipoprotein Apheresis Methods

Therapeutic Apheresis, 2000
Abstract: Low‐density lipoprotein (LDL) apheresis is a treatment option in patients with coronary heart disease and drug resistant hypercholesterolemia. Various apheresis systems based on different elimination concepts are currently in use. We compared the efficacy of 4 different apheresis systems concerning the elimination of lipoproteins.
K G, Parhofer, H C, Geiss, P, Schwandt
openaire   +2 more sources

Low-Density Lipoprotein Apheresis for the Treatment of Refractory Hyperlipidemia

Mayo Clinic Proceedings, 2001
The advent of treatment with 3-hydroxy-3-methylglutaryl coenzyme A inhibitors has meant that, with a combination of diet and drug therapy, adequate control of serum cholesterol concentrations can be achieved in most patients with hypercholesterolemia.
A, Vella, A A, Pineda, T, O'Brien
openaire   +2 more sources

Low‐Density Lipoprotein Apheresis for Focal Glomerular Sclerosis

Therapeutic Apheresis, 1997
Abstract: We report on a 22‐year‐old female with focal glomerular sclerosis and hyperlipidemia who did not respond to long‐term steroid or immunosuppressant therapy. When low‐density lipoprotein (LDL) apheresis was performed, her total daily protein excretion decreased, serum albumin increased, total cholesterol decreased from 1,052 mg/dl to 148 mg/dl
N, Yorioka, Y, Taniguchi, Y, Nishida, S, Okushin, D, Amimoto, M, Yamakido   +5 more
openaire   +2 more sources

Complement Activation During Low‐Density Lipoprotein Apheresis

Artificial Organs, 1992
Abstract: Complement system activation was investigated in two girls with familial homozygous hypercholes‐terolemia undergoing two monthly sessions on LA15 or LA40 (Kaneka liposorber). We determined blood levels of C3c and C3a, leukocyte counts, and plasma levels of C3c and C3a in the extracorporeal circulation device at the start of the sessions and ...
A, Tridon, J B, Palcoux, P, Jouanel, M J, Bezou, M, Coulet, G, Betail   +5 more
openaire   +2 more sources

Low-density lipoprotein apheresis as a treatment option for hyperlipidemia

Current Treatment Options in Cardiovascular Medicine, 2009
Data support the relevance of blood cholesterol levels, particularly high levels of low-density lipoprotein (LDL), in the pathogenesis and progression of atherosclerosis. A strong and continuous relationship between dyslipidemia and vascular morbidity and mortality has been established.
Puja K, Mehta, Jefferson, Baer, Christine, Nell, Laurence S, Sperling   +3 more
openaire   +2 more sources

Low-Density Lipoprotein Apheresis

Lipid-apheresis (LA) and LDL-apheresis (LDLa) are extracorporeal techniques which permit the unselective or specific removal of lipids and lipoproteins, namely Low Density Lipoproteins (LDL), as well as other apolipoprotein B100 (apoB)-containing lipoproteins from plasma -Intermediate Density Lipoproteins, Lipoprotein(a)- [IDL, Lp(a)].
Sumi Hidaka, Shuzo Kobayashi
openaire   +3 more sources