Results 21 to 30 of about 601,516 (329)

LDL-cholesterol to HDL-cholesterol ratio discordance with lipid parameters and carotid intima-media thickness: a cohort study in China

Lipids in Health and Disease, 2020
Background The discordance of the low-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol (LDL-C/HDL-C) ratio with alterative lipid parameters may explain the inconsistent association of CIMT with the LDL-C/HDL-C ratio.
Yanmei Lou, Xue Li, Liming Cao, Pei Qin, Jing Shi, Yanyan Zhang, Changyi Wang, Jianping Ma, Li Wang, Xiaolin Peng, Hongen Chen, Shan Xu, Fulan Hu, Yashuang Zhao, Ping Zhao   +14 more
doaj   +1 more source

Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women. [PDF]

, 2016
BackgroundOptimal macronutrient distribution of weight loss diets has not been established. The distribution of energy from carbohydrate and fat has been observed to promote differential plasma lipid responses in previous weight loss studies, and insulin
Flatt, Shirley W, Heath, Dennis D, Le, Tran, Natarajan, Loki, Pakiz, Bilge, Quintana, Elizabeth L, Rana, Brinda K, Rock, Cheryl L   +7 more
core   +3 more sources

Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S]

Journal of Lipid Research, 2014
Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of hyperlipidemia and recent genome-wide association studies indicate that genetics plays an important role.
Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul   +5 more
doaj   +1 more source

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin, Amento, Edward P, Kong, Raymond, Liu, David, Lundry, Jason, Madasamy, Shanmugavel, Robinson, J Paul, Wu, Alan HB   +7 more
core   +1 more source

Non-high density lipoprotein cholesterol versus low density lipoprotein cholesterol as a discriminating factor for myocardial infarction

BMC Research Notes, 2012
Background Serum total cholesterol (TC) and LDL cholesterol (LDL-C) have been used as major laboratory measures in clinical practice to assess cardiovascular risk in the general population and disease management as well as prognosis in patients. However,
Sigdel Manoj, Yadav Binod, Gyawali Prajwal, Regmi Prashant, Baral Sushil, Regmi Shyam, Jha Bharat   +6 more
doaj   +1 more source

MEDI6012: Recombinant Human Lecithin Cholesterol Acyltransferase, High‐Density Lipoprotein, and Low‐Density Lipoprotein Receptor–Mediated Reverse Cholesterol Transport

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background MEDI6012 is recombinant human lecithin cholesterol acyltransferase, the rate‐limiting enzyme in reverse cholesterol transport. Infusions of lecithin cholesterol acyltransferase have the potential to enhance reverse cholesterol transport and ...
Richard T. George, Liron Abuhatzira, Susan M. Stoughton, Sotirios K. Karathanasis, Dewei She, ChaoYu Jin, Nicholas A. P. S. Buss, Rebecca Bakker‐Arkema, Emily L. Ongstad, Michael Koren, Boaz Hirshberg   +10 more
doaj   +1 more source

Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy. [PDF]

, 2009
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Abhiram Prasad, Amir Lerman, Anderson, Barter, Blake, Bonetti, Cannon, Chait, Charanjit S. Rihal, Colhoun, Cromwell, Deanfield, El Harchaoui, Ford, Forrest, Gurpreet S. Sandhu, Hartman, Hermann, Jeyarajah, Johansson, Joseph P. McConnell, Kathiresan, Kuller, Kuller, Lavi, Lavi, Lerman, Lilach O. Lerman, Mackey, Mackey, Monique A. Ford, Mora, Mora, Otvos, Rosenson, Shahar Lavi, Sirtori, Stacy J. Hartman, Suwaidi, Vakkilainen, van der Steeg, Vergeer, Woodman   +42 more
core   +1 more source

A U-shaped association between the LDL-cholesterol to HDL-cholesterol ratio and all-cause mortality in elderly hypertensive patients: a prospective cohort study

Lipids in Health and Disease, 2020
Background The low-density lipoprotein cholesterol/high-density lipoprotein- cholesterol (LDL-C/HDL-C) ratio is an excellent predictor of cardiovascular disease (CVD).
Yu Yu, Minghui Li, Xiao Huang, Wei Zhou, Tao Wang, Lingjuan Zhu, Congcong Ding, Yu Tao, Huihui Bao, Xiaoshu Cheng   +9 more
doaj   +1 more source

Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]

, 1981
The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW, Brewer, HB, Bronzert, TJ, Forte, T, Lindgren, FT, Niblack, GD, Schaefer, EJ, Starzl, TE, Zech, LA   +8 more
core   +1 more source

Lipoprotein(a) lowering by alirocumab reduces the total burden of cardiovascular events independent of low-density lipoprotein cholesterol lowering: ODYSSEY OUTCOMES trial

European Heart Journal, 2020
Aims Lipoprotein(a) concentration is associated with first cardiovascular events in clinical trials. It is unknown if this relationship holds for total (first and subsequent) events.
M. Szarek, V. Bittner, P. Aylward, M. Baccara-Dinet, Deepak L. Bhatt, R. Diaz, Z. Fras, S. Goodman, S. Halvorsen, R. Harrington, J. Jukema, P. Moriarty, R. Pordy, K. Ray, P. Sinnaeve, S. Tsimikas, R. Vogel, H. White, D. Zahger, A. Zeiher, P. Steg, G. Schwartz   +21 more
semanticscholar   +1 more source