Results 121 to 130 of about 2,502,976 (307)
Water Quality in the Gillham Lake-Cossatot River System During Dry and Wet Periods [PDF]
, 1984 Water samples were collected in the Cossatot River-Gillham Lake system during an extended dry period and after heavy rains to determine the spatial variations in certain water quality characteristics.
Moen, Thomas E., Smith, Stephen B.
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
International Journal of Medicine and Health Development, 2003 Aim: To explore the aetiological factors, pathogenesis and management of priapism and highlight its peculiar features in Nigerians. Materials & Methods: A literature search was carried out using MEDLINE, these were reviewed in line with the aims for ...
Fred O Ugwumba, Aloy E Aghaji
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Antiarrhythmic effect of ischemic preconditioning during low-flow ischemia: The role of bradykinin and sarcolemmal versus mitochondrial ATP-sensitive K+ channels [PDF]
, 2018 . : Short episodes of ischemia (ischemic preconditioning) protect the heart against ventricular arrhythmias during zero-flow ischemia and reperfusion. However, in clinics, many episodes of ischemia present a residual flow (low-flow ischemia).
Barbosa, Vânia +7 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
ThermoTo date, two-phase flow boiling has been extensively investigated for various working fluids and geometries, mainly under operating pressures and mass fluxes in the range of medium to high.
Mehdi Kabir, Corey Field, David Howe
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source