Results 91 to 100 of about 11,576,054 (206)

Aortic Stenosis: The Old Disease With New (and Evolving) Faces

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Calvin Woon‐Loong Chin
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Dobutamine Stress Echocardiography for Management of Low-Flow, Low-Gradient Aortic Stenosis

Journal of the American College of Cardiology, 2018
In the American College of Cardiology/American Heart Association guidelines, patients are considered to have true-severe stenosis when the mean gradient (MG) is ≥40 mm Hg with an aortic valve area (AVA) ≤1 cm2 during dobutamine stress echocardiography (DSE).
Mohamed-Salah, Annabi, Eden, Touboul, Abdellaziz, Dahou, Ian G, Burwash, Jutta, Bergler-Klein, Maurice, Enriquez-Sarano, Stefan, Orwat, Helmut, Baumgartner, Julia, Mascherbauer, Gerald, Mundigler, João L, Cavalcante, Éric, Larose, Philippe, Pibarot, Marie-Annick, Clavel   +13 more
openaire   +2 more sources

The Role of CT in Assessing the Degree of Aortic Valve Calcification and the Severity of Aortic Valve Stenosis

Инновационная медицина Кубани
Objective: To evaluate the role of computed tomography in determining the degree of calcification and the severity of aortic valve stenosis.Material and methods: In total, 118 patients with an indication for transcatheter aortic valve implantation, in ...
B. E. Gafsi, A. V. Shirkin, S. K. Ternovoy   +2 more
doaj   +1 more source

LES of non-Newtonian physiological blood flow in a model of arterial stenosis [PDF]

, 2012
Large Eddy Simulation (LES) is performed to study the physiological pulsatile transition-to-turbulent non-Newtonian blood flow through a 3D model of arterial stenosis by using five different blood viscosity models: (i) Power-law, (ii) Carreau, (iii ...
Molla, M.M., M.C. Paul, M.M. Molla, Paul, M.C.   +3 more
core   +1 more source

Relationship Between QT Interval and Outcome in Low‐Flow Low‐Gradient Aortic Stenosis With Low Left Ventricular Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundQT interval has been shown to be associated with cardiovascular events. There is no data regarding the association between QT interval and left ventricular (LV) function and prognosis in patients with low LV ejection fraction (LVEF), low‐flow ...
Abdellaziz Dahou, Oumhani Toubal, Marie‐Annick Clavel, Jonathan Beaudoin, Julien Magne, Patrick Mathieu, François Philippon, Jean G. Dumesnil, Rishi Puri, Henrique B. Ribeiro, Éric Larose, Josep Rodés‐Cabau, Philippe Pibarot   +12 more
doaj   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation. [PDF]

, 2015
BACKGROUND Up to 1 in 6 patients undergoing transcatheter aortic valve implantation (TAVI) present with low-ejection fraction, low-gradient (LEF-LG) severe aortic stenosis and concomitant relevant mitral regurgitation (MR) is present in 30% to 55% of ...
Heg, Dik, Windecker, Stephan, Buellesfeld, Lutz, Praz, Fabien, Zbinden, Stephan, Wenaweser, Peter Martin, Wenaweser, Peter, Stortecky, Stefan, Büllesfeld, Lutz, Khattab, Ahmed Aziz, Huber, Christoph, Carrel, Thierry, Zanchin, Thomas, O'Sullivan, Crochan J, Pilgrim, Thomas, Blöchlinger, Stefan, Khattab, Ahmed A, Meier, Bernhard, Bütikofer, Anne   +18 more
core   +2 more sources

Protosappanin A Alleviates Atherosclerosis by Regulating the MDM2/GPX4 Axis‐Mediated Endothelial Ferroptosis

Phytotherapy Research, EarlyView.
PTA alleviates atherosclerosis by regulating the MDM2/GPX4 axis‐mediated endothelial ferroptosis. ABSTRACT Endothelial ferroptosis is a crucial pathogenic driver of atherosclerosis (AS) progression. Protosappanin A (PTA), a bioactive compound from Caesalpinia sappan L., protects cardiovascular vessels by regulating ferroptosis.
Jiamei Fu, Lin Zhu, Wenwei Yang, Mengnan Li, Zhixin Wu, Shude Sun, Yabin Zhou   +6 more
wiley   +1 more source

Workup and Management of Patients With Paradoxical Low-Flow, Low-Gradient Aortic Stenosis

Current Treatment Options in Cardiovascular Medicine, 2018
About 60% of patients with paradoxical low-flow, low-gradient (PLF-LG) aortic stenosis (AS) have a severe disease that justifies aortic valve replacement (AVR). The first step in patients with symptomatic PLF AS should be to rule out measurement errors and treat hypertension.
Mohamed-Salah, Annabi, Marine, Clisson, Marie-Annick, Clavel, Philippe, Pibarot   +3 more
openaire   +3 more sources