Results 101 to 110 of about 11,576,054 (206)

Low-Gradient, Low-Flow Severe Aortic Stenosis With Preserved Left Ventricular Ejection Fraction Characteristics, Outcome, and Implications for Surgery [PDF]

, 2015
BackgroundSevere low-gradient, low-flow (LG/LF) aortic stenosis with preserved left ventricular ejection fraction (EF) has been described as a more advanced form of aortic stenosis. However, the natural history and need for surgery in patients with LG/LF
Maizel, Julien, Kamel, Said, Debry, Nicolas, Slama, Michel, Mentaverri, Romuald, Tribouilloy, Christophe, Rusinaru, Dan, Maréchaux, Sylvestre, Castel, Anne-Laure, Lévy, Franck   +9 more
core   +1 more source

Sleep‐disordered breathing in valvular heart disease: A Modifiable comorbidity

Sleep Research, EarlyView.
Abstract Sleep‐disordered breathing (SDB) is highly prevalent among patients with valvular heart disease (VHD) and is independently associated with adverse clinical outcomes. The two major phenotypes—obstructive sleep apnea (OSA) and central sleep apnea (CSA)—exhibit distinct distributions across VHD subtypes. CSA predominates in severe aortic stenosis,
Wu Juan, Chen Ze, Zhang Qun, Chen Qiuyuan, Su Mei, Zhang Xilong, Ding Ning   +6 more
wiley   +1 more source

Cost-utility of transcatheter aortic valve implantation for inoperable patients with severe aortic stenosis treated by medical management: a UK cost-utility analysis based on patient-level data from the ADVANCE study. [PDF]

, 2014
OBJECTIVE: To use patient-level data from the ADVANCE study to evaluate the cost-effectiveness of transcatheter aortic valve implantation (TAVI) compared to medical management (MM) in patients with severe aortic stenosis from the perspective of the UK ...
Busca, R, Axel Linke, Amie Padhiar, Peter Wenaweser, Neil Moat, Piazza, N, Stuart Mealing, Johan Bosmans, Mealing, S, Stephen Brecker, Mark Sculpher, Ulrich J Gerckens, Nicolo Piazza, Rachele Busca, Padhiar, A, Sabine Bleiziffer, Tamburino, C, Sculpher, M, Bosmans, J, Gerckens, UJ, Bleiziffer, S, Linke, A, James Eaton, Eaton, J, Wenaweser, P, Moat, N, Corrado Tamburino, Brecker, S, Brecker, Stephen, Mealing, Stuart, Padhiar, Arnie, et al., Bosmans, Johan   +32 more
core   +1 more source

PDA‐Engineered 3D‐Printed Polymer–ZrO2 Hybrid Scaffolds Enabling Enhanced Radiopacity, Photothermal Therapy, and Cell Migration Modulation

Small, EarlyView.
A multifunctional 3D‐printed polymer–ZrO2 scaffold is developed to provide intrinsic radiopacity, photothermal responsiveness, and surface bioactivity. Reinforcement with ZrO2 enables real‐time x‐ray visibility and mechanical robustness, while a polydopamine coating facilitates near‐infrared‐triggered drug release and modulates cell migration, thereby ...
Sumin Kang, Yun‐Jin Jeong, Seokjae Kim, Van Du Nguyen, Songah Jeong, Juyeong Jo, Arunkumar Shanmugasundaram, Jin Uk Jeong, Dong‐Weon Lee, Eunpyo Choi, Hyungwoo Kim   +10 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Outcomes From Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis and Left Ventricular Ejection Fraction Less Than 30%: A Substudy From the TOPAS-TAVI Registry.

, 2019
Importance In low-flow, low-gradient aortic stenosis (LFLG AS), the severity of left ventricular dysfunction remains a key factor in the evaluation of aortic valve replacement.
Garcia Del Blanco, Bruno, Rodés-Cabau, Josep, Zajarias, Alan, Gleason, Thomas G, Salah-Annabi, Mohammed, Babaliaros, Vasilis, Puri, Rishi, Enriquez-Sarano, Maurice, Hayek, Salim, Nombela-Franco, Luis, Clavel, Marie-Annick, Maes, Frédéric, Pibarot, Philippe, Barbosa Ribeiro, Henrique, Schindler, John T, Chakravarty, Tarun, Windecker, Stephan, Le Ven, Florent, Lerakis, Stamatios, Cavalcante, João L, Cheema, Asim N, Amat-Santos, Ignacio, Serra, Vicenç, de Agustin, Alberto, Lisko, John C, Dahou, Abdellaziz, Makkar, Raj, Muñoz-García, Antonio J, Côté, Melanie, Gilard, Martine, Szeto, Wilson, Herrmann, Howard C, Pelletier-Beaumont, Emilie   +32 more
core   +1 more source

Transcatheter Aortic Valve Implantation in Severe Left Ventricular Dysfunction: A Viable Option in a Patient With Low-Flow, Low-Gradient Critical Aortic Stenosis [PDF]

, 2013
Images are provided from a successful procedure of transcatheter aortic valve implantation (TAVI) in an elderly patient with symptomatic low-flow, low-gradient critical aortic stenosis, and associated severe left ventricular dysfunction, who had a very ...
Dedeilias, Panagiotis, Rouska, Effie, Bethanis, Spyros, Polydorou, Antonios, Kokotsakis, John, Minos, Theofanis, Manolis, Antonis S   +6 more
core   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Deep Learning‐Based Dynamic Segmentation of the Left Atrium in 4D Flow MRI

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2505-2515, November 2026.
ABSTRACT Purpose To design a deep learning pipeline for automated, time‐resolved segmentation of the left atrium (LA) from 4D flow MRI data. Methods We studied 100 individuals including 65 patients with atrial fibrillation (AF) and 35 healthy subjects (HS) resulting in 2530 4D flow MRI time‐volumes acquired in different centers and scanners.
Jonas Leite, Tom Da‐Silva Faria, Marie Shannon Soulez, Khaoula Bouazizi, Perrine Marsac, Elie Mousseaux, Jérôme Lamy, Moussa Gueda Moussa, Olivier Piot, Jacques Feignoux, Daniel Giese, Nicolas Badenco, Estelle Gandjbakhch, Alban Redheuil, Mikaël Laredo, Emilie Bollache, Nadjia Kachenoura   +16 more
wiley   +1 more source

Hemodynamic Assessment of Patients With Low-Flow, Low-Gradient Valvular Aortic Stenosis

The American Journal of Cardiology, 1996
In aortic stenosis (AS), conventional indexes of severity vary with changes in transvalvular flow. It is important to determine the true severity of obstruction because AS in the presence of low cardiac output and low gradient is associated with high mortality during aortic valve replacement.
L R, Blitz, H C, Herrmann
openaire   +2 more sources